half agony, half hope

#usercaro, late 20s, tired gifs, lb, spotify

[paramores]

tv shows used to have hot guys and by hot guys i mean chad michael murray

[macgyvermedical]

When Drugs Became Available

Have you ever been writing some historical fiction and wondered "hey, I wonder if my characters would have been able to pop an ibuprofen in 1977?" Well, you're in luck, because this post is all about when common medications became available:

Acetaminophen: 1950

Albuterol: 1969 (UK) 1982 (US)

Allopurinol: 1966

Alprazolam: 1981

Amitriptyline: 1961

Amlodipine: 1990

Amoxicilin: 1972

Amphetamine/Dextroamphetamine (together as Adderall): 1996

Apixiban: 2012

Aripiprazole: 2002

Aspirin (first NSAID): 1899

Azidothymidine (first antiviral): 1987

Barbital (first barbiturate): 1903

Bupropion: 1985

Buspirone: 1986

Calcium Carbonate (TUMS): 1930

Captopril (first ACE inhibitor): 1981

Chlordiazepoxide (first benzodiazepine): 1960

Chlorothiazide (first thiazide diuretic): 1957

Chlorpromazine (first antipsychotic): 1952

Cyclobenzeprine: 1977

Diphenhydramine: 1946

Furosemide: 1959

Fluoxetine (first SSRI): 1988

Gabapentin: 1993

Glipizide: 1984

Hydrochlorothiazide: 1959

Ibuprofen: 1969 (UK) 1974 (US)

Insulin: 1923 (though many types of insulins would become available over the next century)

Imipramine (first tricyclic antidepressant): 1959

Iproniazid (first antidepressant (MAOI)): 1952

Levothyroxine: 1927 (though desiccated pork thyroid was used for the same reasons as early as 1890)

Lisinopril: 1987

Lithium: 1949

Losartan (first ARB): 1995

Lovastatin (first statin): 1987

Naproxen: 1976 (Rx) 1990 (OTC)

Nitrogen Mustard (first chemotherapy agent): early 1940's

Methotrexate: 1947

Methylphenidate: 1954

Metformin: 1957 (France) 1995 (US)

Metoprolol: 1978

Montelukast: 1998

Morphine: early 1800's

Omeprazole: 1989

Penicillin: 1945

Phenbezamine (first antihistamine): 1942

Prednisone: 1955

Propranolol (first beta blocker): 1965 (UK) 1967 (US)

Sertraline: 1990

Spironolactone: 1959

Sulfanilamide (first modern antibiotic): 1935

Tolbutamide (first oral anti-diabetic drug): 1956

Tramadol: 1977 (Germany) 1995 (US)

Trazodone: 1981

Valacyclovir: 1995

Verapamil (first calcium channel blocker): 1964

Warfarin: 1954

Zopiclone (first "Z-drug"): 1986

[macgyvermedical]

Someone asked for this list in date order, so here it is!

Morphine: early 1800's

Aspirin (first NSAID): 1899

Barbital (first barbiturate): 1903

Insulin: 1923 (though many types of insulins would become available over the next century)

Levothyroxine: 1927 (though desiccated pork thyroid was used for the same reasons as early as 1890)

Calcium Carbonate (TUMS): 1930

Sulfanilamide (first modern antibiotic): 1935

Nitrogen Mustard (first chemotherapy agent): early 1940's

Phenbezamine (first antihistamine): 1942

Penicillin: 1945

Diphenhydramine: 1946

Methotrexate: 1947

Lithium: 1949

Acetaminophen: 1950

Chlorpromazine (first antipsychotic): 1952

Iproniazid (first antidepressant (MAOI)): 1952

Methylphenidate: 1954

Warfarin: 1954

Prednisone: 1955

Tolbutamide (first oral anti-diabetic drug): 1956

Chlorothiazide (first thiazide diuretic): 1957

Metformin: 1957 (France) 1995 (US)

Furosemide: 1959

Hydrochlorothiazide: 1959

Spironolactone: 1959

Imipramine (first tricyclic antidepressant): 1959

Chlordiazepoxide (first benzodiazepine): 1960

Amitriptyline: 1961

Verapamil (first calcium channel blocker): 1964

Propranolol (first beta blocker): 1965 (UK) 1967 (US)

Allopurinol: 1966

Albuterol: 1969 (UK) 1982 (US)

Ibuprofen: 1969 (UK) 1974 (US)

Amoxicilin: 1972

Naproxen: 1976 (Rx) 1990 (OTC)

Cyclobenzeprine: 1977

Tramadol: 1977 (Germany) 1995 (US)

Metoprolol: 1978

Captopril (first ACE inhibitor): 1981

Trazodone: 1981

Alprazolam: 1981

Glipizide: 1984

Bupropion: 1985

Buspirone: 1986

Zopiclone (first "Z-drug"): 1986

Lovastatin (first statin): 1987

Azidothymidine (first antiviral): 1987

Lisinopril: 1987

Fluoxetine (first SSRI): 1988

Omeprazole: 1989

Amlodipine: 1990

Sertraline: 1990

Gabapentin: 1993

Losartan (first ARB): 1995

Valacyclovir: 1995

Amphetamine/Dextroamphetamine (together as Adderall): 1996

Montelukast: 1998

Aripiprazole: 2002

Apixiban: 2012

[paramores]

lady bird is such a perfect movie fr

[cinnamonbarbies]

Drew Barrymore at the Ever After premiere 1998

[apatheticfluorescence]

some hyper famous artists like Van Gogh transcend overratedness and become underrated because they're so normalized. Like I'll look at a van Gogh and I'm like wait this really is amazing you guys don't get it

[headspace-hotel]

Shakespeare is like this

[insufferablepirate]

Every time I see a Van Gogh that’s not one of his better known pieces it absolutely blows me away

Have you seen this shit my liege? smh unreal

[louferrignojrofficial]

JONAH + AMY

[oliviasource]

OLIVIA RODRIGO the cure (behind the scenes)

[lakevida]

i think its charming when peoples personal lives improve and they get drastically worse at posting

[ms-demeanor]

How do you feel about driving?

I can drive, I am good at driving, I enjoy driving.

I can drive, I am good at driving, I do not enjoy driving.

I can drive, I am bad at driving, I enjoy driving.

I can drive, I am bad at driving, I do not enjoy driving.

I haven't learned to drive, I think I would enjoy driving.

I haven't learned to drive, I do not think I would enjoy driving.

I can't drive anymore, I was good at it, I enjoyed driving.

I can't drive anymore, I was good at it, I didn't enjoy it.

I can't drive anymore, I was bad at it, I enjoyed it.

I can't drive anymore, I was bad at it, I didn't enjoy it.

Remaining time: 22 hours 46 minutes

[paramores]

i think i also want to start my journey to get a personal trainer certification… 👩🏻‍🦯

[pitchburgh]

good or not, would anyone else WANT your url?

MANY people would want my Tumblr handle

a small handful of folks might want my Tumblr handle

I'm the only one who wants my url (positive)

Honestly? I don't even want this url myself

Voting ended onJun 1

[sulietsexual]

Clark Kent + 😁😁😁 Requested by Anonymous

[robbiegk]

BAD BUNNY Rolling Stone — Eric Rojas (2025)

[sik3rning]

squidward cleaning your filthy ass blog

[polish-lolita]

[connorwyndham]

Matthew Perry and Matt LeBlanc as Chandler Bing and Joey Tribbiani FRIENDS (1994 – 2004)

God, it's gonna so weird like when I come home and you're not here.

[rylandsgrace]

Project Hail Mary (2026) // Barbie (2023)