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Nitrofurantoin, sulfas, NSAIDs, PCN, thiazides, TCAs, hydralazine, chlorpromazine among others are associated with eosinophilic pulmonary reactions.

#eosinophilic #Pulmo

Amiodarone can cause ARDS (at initiation) and pulmonary fibrosis (later)

#amiodarone #ARDS #fibrosis

All of the following drugs can cause eosinophilic pneumonia except : (A) nitrofunatoin (B) sulfonamides (C) NSAIDs (D) isoniazid (E) amiodarone

#quiz

Lytics should be considered when Pulmonary Embolism causes: 1) Persistent hypotension (SBP <90mmHg) 2) Severe hypoxemia 3) Large perfusion defect 4) RV dysfunction 5) Freefloating RV thrombus 6) PFO

Lymphoid granulomatosis almost always has pulmonary involvement, and in case reports can mimic Wegener’s

#granulomatosis #wegener's

Many malignancies are associated with EBV, including Burkett’s (classic association), Hodgkin’s disease, HIV-associated lymphomas, and post-transplant lymphoproliferative disorders.

#ebv #burkett's #hodgkin's

Lymphoid granulomatosis is an EBV associated angiodestructive lymphoproliferative disorder associated with the triad of nodular polymorphic lymphoid infiltrates (small lymphocytes, plasma cells, large atypical mononuclear cells, and vigorous T-cell response), angiitis (due to infiltration by lymphocytes), and granulomatosis

#granulomatosis #EBV #lymph #angitis

EKG findings in Pulmonary Embolism include: S1Q3T(inverted)3 , sinus tachycardia, RBBB, RAD, ST changes, T-wave changes and new onset a-fib

#cardio #PE #EKG

Pulmonary embolism - In addition to the usual glossitis, dermatitis and stomatitis - zinc deficiency, particularly severe deficiency, is manifested by depressed immune function, bullous pustular dermatitis, diarrhea and alopecia.

#PE #zinc #dermatitis #stomatitis #glossitis #aloepecia #diarrhea #IM #Pulmo

Prostate, Breast & Lung mets account for 80% of bony mets. Kidney, bladder, thyroid, lymphomas and sarcomas also commonly metastasize (incl. to bone). Hypercalcemia is common with destructive lesions.

#Onco #bonymets

A primary tumor of colon is least likely to metastasize to bone

#Onco #metastasis #bonymets

PNH (Paroxysmal nocturnal thrombosis) - APML = anemia, thrombocytopenia and leukocytosis or leucopenia with DIC

#PNH #APML #Cardio #Dx

PNH (Paroxysmal nocturnal thrombosis) - Leptospirosis = fevers, hyperbilirubinemia & ARF

#PNH #Cardio #Dx

PNH (Paroxysmal nocturnal thrombosis) - Both HUS & TTP cause hemolysis, thrombocytopenia & fevers; renal failure is more common in HUS; cerebrovascular events & mental status changes are more common in TTP

#PNH #Cardio #HUS #TTP

PNH (Paroxysmal nocturnal thrombosis) = anemia, granulocytopenia & thrombocytopenia. Venous thrombosis is common (cerebral sinus thrombosis is most common cause of death). The triad of portal vein thrombosis, hemolysis, and pancytopenia suggests PNH.

#PNH #anemia #Dx #Cardio

PNH (Paroxysmal nocturnal thrombosis) - Ham or sucrose lysis test is diagnostic (remember PNH is stem-cell derived intracorpuscular defect); can test for GPI-linked proteins CD55 and CD59 on RBCs and granulocytes

#PNH #Dx #CD55 #CD59 #cardio

Re Pott's, the lower thoracic spine & upper lumbar spine are most commonly affected in adults. Diagnosis of Pott’s is best done via aspiration of the infected area

#Pott's #Dx

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