Aphmau is one of my favorite youtubers. I have a bunch of theories that go to Aphmau's different shows. One of my theories is that the Aphmau from Dreams of Estorra is the original Aphmau. (If you have not watched that show please go and watch it! It is amazing!! Now the reason for this is because she wants somewhere to belong and is actively trying to learn. Now lady Irene is the oddest version of Aphmau that we know of so far. And is a piece of Aphmau's soul, which I get into more in another theory. We all know that Irene was once human so that would mean at one point lady Irene had to learn how to use magic and have a reason to help others. Any Aphmau is kind at heart and will help out anyone ( unless it is an upside down Aphmau). How I think Aphmau from D.o.E. is the original is that in the future of Dreams of Estorra. Aphmau will either become a member of Estorra and the world reset or go to a whole new world/realm. And from all her training with resin become a low level master at magic and will be able to use magic without resin or be connected to a Heart Tree. The 2 reasons why I think dreams of estorra is connected to mcd and My street is because in season 5, Oscar is seen on a wall with the other "relics" that tied My street to mcd. The second one is in void paradox, a lot of the mindless people look like they were from Estorra and the other knight that helped Aph, also seems to be from Estorra.
Edit: Middlebrother also thinks EoD and My street are connected and have great reasons!!