Abiraterone Tablet 250 mg: Essential Guide to Uses, Side Effects, and Precautions
Understanding Abiraterone
Abiraterone acetate 250 mg tablets are a breakthrough oral medication in the fight against advanced prostate cancer. This powerful anti-androgen medication has revolutionized treatment options for men with metastatic prostate cancer, offering extended survival and improved quality of life when traditional therapies are no longer effective. Quality pharmaceutical manufacturers like Medyra Pharma are committed to making this life-saving medication accessible to patients worldwide through their high-standard production facilities.
Primary Uses and Indications
Abiraterone 250 mg tablets are specifically prescribed for treating:
Metastatic Castration-Resistant Prostate Cancer (mCRPC): Used when the cancer has spread beyond the prostate and continues to grow despite low testosterone levels from standard hormone therapy.
Metastatic Castration-Sensitive Prostate Cancer (mCSPC): Prescribed for newly diagnosed high-risk patients in combination with other hormone therapies.
The medication works by inhibiting the CYP17 enzyme, effectively blocking androgen production throughout the body – in the testes, adrenal glands, and tumor tissue itself. This comprehensive approach starves cancer cells of the hormones they need to grow and multiply.
Dosage and Administration
The standard dosage is 1000 mg daily (four 250 mg tablets) taken as a single dose on an empty stomach. Patients must avoid food for at least two hours before and one hour after taking the medication. Abiraterone is typically prescribed alongside prednisone (5 mg twice daily) to manage potential side effects and enhance effectiveness.
Key administration points:
Swallow tablets whole with water
Take at the same time each day
Never crush or break tablets
If a dose is missed, resume regular schedule the next day
While generally well-tolerated, patients may experience various side effects ranging from mild to severe:
Most Common (>30% of patients):
Fluid retention in legs and feet
Moderate Frequency (10-30% of patients):
Digestive issues (diarrhea, constipation)
Cough and upper respiratory infections
Regular monitoring is crucial for patients taking Abiraterone. Healthcare providers typically conduct:
Liver function tests before treatment and frequently during the first three months
Monthly potassium level checks to prevent dangerous imbalances
Blood pressure monitoring throughout treatment
Blood sugar monitoring for diabetic patients
Contraindications: Abiraterone must not be used by women, especially those pregnant or potentially pregnant, as it can cause severe fetal harm. Men taking this medication should use contraception if their partner could become pregnant.
Drug Interactions: Patients should inform their healthcare provider about all medications, as Abiraterone can interact with various drugs, particularly those metabolized by certain liver enzymes.
Food Interactions: The absorption of Abiraterone increases significantly with food, potentially causing adverse effects. Strict adherence to empty stomach administration is essential.
Quality and Accessibility
When it comes to critical cancer medications like Abiraterone, choosing a reliable pharmaceutical source is paramount. Medyra Pharma stands out in the pharmaceutical industry by maintaining stringent quality control measures and adhering to international manufacturing standards, ensuring patients receive safe and effective medication for their treatment journey.
Success with Abiraterone therapy requires:
Consistent medication timing
Regular medical appointments
Immediate reporting of unusual symptoms
Maintaining prescribed prednisone therapy
Staying hydrated and monitoring weight
Patients should contact their healthcare provider immediately if experiencing severe fatigue, yellowing of skin or eyes, severe swelling, chest pain, or irregular heartbeat.
Store Abiraterone at room temperature (68-77°F) in its original container, protected from moisture and light. Keep out of reach of children and pets. Pregnant women should avoid handling crushed or broken tablets.
Abiraterone 250 mg tablets offer hope for men with advanced prostate cancer, providing meaningful life extension and symptom control. With trusted pharmaceutical partners like Medyra Pharma working to ensure medication availability and quality, patients can focus on their treatment journey with confidence. While side effects require careful management, most patients tolerate the treatment well with proper monitoring and support.
