In the past years, ABO blood group incompatibility was regarded as an absolute contraindication for kidney transplantation. However, there has been a progress in the defined desensitization practice and immunologic understanding, allowing increasingly successful ABO incompatible transplantation during recent years. There are some information on disserted outcomes, the history, desensitization modalities and protocols, posttransplant immunologic surveillance. You also can know the information of antibody-mediated rejection in transplantation with an ABO incompatible kidney allograft. Nowadays, the liver transplantation is the most effective treatment of end-stage renal disease, but the doctors may be faced with the ABO incompatibility problems.
The ABO incompatibility transplant aims to overcome the profound donor shortage. A transplant can be successfully done even if the organ donor and recipient had incompatible blood types. A few years ago, an estimated 30% of patients who are needing a new kidney were turned down because of the blood incompatibility issues. However, a transplant team is capable of breaking the ABO incompatibility barrier through the innovative new procedures. In other words, you can have one if you previously had no access to a kidney transplant. The fact is that the success rates are as high as transplant performed with blood-type-compatible recipients and donors.