Biphasic Effects on Allergen-Specific Type 2 Memory B Cells Over 18 Months Sublingual Immunotherapy for House Dust Mite Allergy - Research
Background: Type 2 memory B cells (Bmem) are the reservoir of pathogenic IgE in allergies. Allergen immunotherapy (AIT) can change the course of disease, but if it involves reprogramming of allergen-reactive Bmem remains unknown. Here, we examine how AIT affects allergen-specific Bmem in house dust mite (HDM) allergic patients. Methods: HDM allergic patients were longitudinally evaluated over…















