#annulus fibrosus

[cbotella]

The Role of Hypoxia in Angiogenesis and Extracellular Matrix Regulation of Intervertebral Disc Cells During Inflammatory Reactions

Neurosurgery 81:867–875, 2017

The intervertebral disc (IVD) is an avascular structure, and is therefore stable under hypoxic conditions. Previous studies have demonstrated that hypoxia might be related to symptomatic degenerative disc diseases (DDDs); however, the pathomechanism is still poorly understood.

OBJECTIVE: To identify the effect of hypoxia on the production of inflammatory mediators,…

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[cbotella1]

The Role of Hypoxia in Angiogenesis and Extracellular Matrix Regulation of Intervertebral Disc Cells During Inflammatory Reactions

Neurosurgery 81:867–875, 2017

The intervertebral disc (IVD) is an avascular structure, and is therefore stable under hypoxic conditions. Previous studies have demonstrated that hypoxia might be related to symptomatic degenerative disc diseases (DDDs); however, the pathomechanism is still poorly understood.

OBJECTIVE: To identify the effect of hypoxia on the production of inflammatory mediators,…

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[mburatov]

Stem Cell Treatment for Degenerative Disc Disease

Stem Cell Treatment for Degenerative Disc Disease

A new analysis of stem cell trials that targeted degenerative disc disease of the spine in animals has shown that these treatments are effective in halting or even reversing this disease. Such results should facilitate the implementation of human clinical trials.

Our spinal cords are encased in a protective body of bone known as the vertebral column. The vertebral column consists of a stack of…

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