Toast, what the worst mission yall been on?
Oh, hello Sally! I hope you're doing well.
Hmmn. To answer your question, we've definitely had. Struggles. Some I don't particularly wish to recount.
But off the top of my head, (and of course I can't speak for Ghost), but once we had to deal with a slug. An interdimensional, gigantic slug, in a dimension consisting only of mud. And we were entirely unprepared— I was driving when the portal opened up. We were only able to recover my car after the slug exploded and covered everything in. Slug-goo. Including us.
I lost track of how many showers I had to take after, and how many hours it took to wash our clothes. I remember Ghost suggesting we burn them.
Maybe it's not too late, now that I'm thinking about it...