#basic medium

[abdullahaydogan]

HYDROXIDE-ION-PROMOTED ESTER HYDROLYSIS

The rate of hydrolysis of an ester can be increased by hydroxide ion. Like an acid catalyst, hydroxide ion increases the rates of the two slow steps of the reaction—namely, formation of the tetrahedral intermediate and collapse of the tetrahedral intermediate.

MECHANISM FOR THE HYDROXIDE-ION-PROMOTED HYDROLYSIS OF AN ESTER