#binol

[waterdnp]

side note i filmed binol!! depending on how busy i am and what my school schedule is tomorrow it may be out by the end of this week but if not probably by the beginning of next week :) 

[labphoto]

Some ( R)-(+) and (S)-(-) BINOL ( [1,1’-binaphthalene]-2,2’-diol) under toluene what was used to recrystallize them.

For chemists, the R / S system is the most important nomenclature system for denoting enantiomers, which does not involve a reference molecule such as glyceraldehyde. It labels each chiral center R or S according to a system by which its substituents are each assigned a priority, according to the Cahn–Ingold–Prelog priority rules (CIP), based on atomic number. If the center is oriented so that the lowest-priority of the four is pointed away from a viewer, the viewer will then see two possibilities: If the priority of the remaining three substituents decreases in clockwise direction, it is labeled R (for Rectus, Latin for right), if it decreases in counterclockwise direction, it is S (for Sinister, Latin for left).

An enantiomer can be named by the direction in which it rotates the plane of polarized light. If it rotates the light clockwise (as seen by a viewer towards whom the light is traveling), that enantiomer is labeled (+). Its mirror-image is labeled (−).

For more: https://en.wikipedia.org/wiki/Chirality_(chemistry)

[labphoto]

Since we have no money to buy optically pure BINOL ( [1,1’-binaphthalene]-2,2’-diol) I made some. Here in the flask is some raw ( R)-(+)-BINOL.

It’s quite interesting that optically pure BINOL forms quite different shaped crystals than the racemic one. From now just a quick recrystallization from toluene and I’ve finally got some +95% optically pure product (confirmed by polarimetry). 

[labphoto]

Something what was requested at least 100 times from the followers: separation of non miscible organic and aqueous phases. 

Since we have no money to buy optically pure BINOL ( [1,1'-binaphthalene]-2,2'-diol) I have to synthesize it from ß-naphthol in a 3 step synthesis. On the gif there is the last step of the synthesis, just after the resolution. Here I decomposed the diastereomeric salt with a lye solution and in the upper ethyl-acetate phase there is the optically pure (R)-(+)-1,1′-Bi(2-naphthol). I just need to separate the phases and evaporate to get the pure product.