Research reveals a new secret to the miracle of breast milk
One of the secrets to rich milk production in lactation has been uncovered by researchers at the Walter and Eliza Hall Institute. Their studies have revealed that breast cells develop two nuclei as the breast switches on lactation to nurture the newborn.
This change begins to occur in late pregnancy with the generation of vast numbers of cells with two nuclei.
The research was led by Professor Jane Visvader, Professor Geoff Lindeman, Dr Anne Rios and Dr Nai Yang Fu, from the institute’s ACRF Stem Cells and Cancer Division, and shows that these cells with two nuclei disappear at the cessation of lactation, when breast cells return to a single nucleus state. It is published today in the journal Nature Communications.
Using unique 3-D imaging technology Dr Rios and Dr Fu found huge numbers of cells became binucleated – developed a second nucleus – a process that is critical to milk production.
Professor Visvader said the process – which lasts only for the duration of lactation – was important for the newborn to thrive when breast milk was the sole nutrient.