Gene Mutation and BRCA screening - Early Diagnosis is a key to Prevention
Genetic Mutations and its causes:
Genes make proteins which are responsible for the proper functioning of the body. The process of translation processes the proteins. Any hindrance in this process leads to faulty production of proteins which in turn results in the development of severe health complication or disease in an individual. These hindrances can be called as genetic mutations. Mutations are usually defined as certain changes in the DNA carried by genes due to external or internal factors. These mutations alter the normal functioning of the gene and results in the development of genetic disorders, diseases and chromosomal abnormalities. Lifestyle changes and diet pattern may also cause certain mutation the genetic material of an individual resulting in severe health diseases.
BRCA Mutation and Genetic Screening:
BRCA genes are present normally in an individual and function as tumour suppressor genes. These genes do not allow the development of tumour in the body of the individual. These genes participate in DNA repair mechanism and prevent any kind of alteration in the structure of DNA. However, the functioning of BRCA genes changes if they are get altered due to genetic mutation. Any mutation in the BRCA genes changes the behaviour of genes and these genes instead of preventing the growth of a tumour; they help in the development of breast and ovarian cancer in the body of females. Even males also have an equal chance of developing breast cancer. Screening for genetic mutations in BRCA genes using genetic testing can help the doctors in early diagnosis of breast cancer. If an individual is found to be BRCA positive, the individual may be at high risk for developing breast cancer. At this point of time, the individual can meet his physician and discuss the changes that need to be adapted in order to lower down the risk of breast cancer.
Genetic testing and BRCA Check:
BRCA testing is crucial as it helps in estimating the risk of an individual for the development of breast and ovarian cancer. Different diagnostic labs present across the nation conduct BRCA genetic testing. Very few of them are recognized and provide reliable and accurate results. Genes2Me, one of recognized genetic testing laboratory offering solutions in advanced molecular diagnostics, provide BRCA testing for BRCA1 and BRCA2 genes. The company has a dedicated BRCA panel which screens for mutated BRCA genes in the genome of an individual. Using Next-Generation Sequencing technology, the genome of the individual is scanned, and BRCA mutated genes are identified. An advanced panel of BRCA also focuses on other genes other than BRCA that may put an individual at risk for the development of breast cancer. The test offers exceptional sensitivity, specificity and accuracy in the delivery of results. Pre and post genetic counselling options are provided by Genes2Me so that customers can know meaningful findings from the test reports. The counsellor guides the individual with preventive strategies and also help in estimating the risk of Breast cancer in the family.
Early diagnosis using BRCA genetic testing can help in estimating the risk of breast and ovarian cancer and can also help the doctors in designing effective treatment strategies.
