Jan 4, 2021
Brittany Nelson
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Brittany Nelson
InChem Corp. has the capability to support scale-up for a wide range of chemical process, all on one site in Rock Hill, SC. Learn more.
InChem Corporation has the capability to support scale-up for various types of chemical process, all on one site in Rock Hill, SC. From the laboratory, to the pilot plant, to smaller reactors, to full scale, InChem is ready to support your development efforts. Read more.
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Report on Chemical Process Simulators Market Size, Status and Forecast 2022
Report on Chemical Process Simulators Market Size, Status and Forecast 2022
The global Chemical Process Simulators market, analyzes and researches the Chemical Process Simulators development status and forecast in United States, EU, Japan, China, India and Southeast Asia. Browse Market Research Report @ www.reportsandmarkets.com/reports/global-chemical-process… Chemical Process Simulators report focuses on the top players in global market, like Avtech Scientific, Aspen…
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Researchers found a new class of antibiotics
New Post has been published on http://spinonews.com/2017/06/04/researchers-found-a-new-class-of-antibiotics/
Researchers found a new class of antibiotics
New class of antibiotics
Scientists developed a novel chemical process that may lead to the creation of a new class of antibiotics.
The discovery comes at a time when more types of bacteria are becoming resistant to existing antibiotics, increasing the occurrence of lethal infections.
The ability to create new antibiotics would have significant ramifications for medical treatment and public health.
Seth Herzon, a chemistry professor at Yale, said, this is one way to focus our talents as synthetic chemists in a direction that can immediately help patients.
Pleuromutilin
The new process makes it possible to create molecules related to the natural product pleuromutilin from simple commercial chemicals in the laboratory.
Pleuromutilin is produced by a fungus and was found to have useful antibacterial properties in the early 1950s.
A new miracle material could end cracked smart devices
Since then, scientists in academia and the pharmaceutical industry have created thousands of pleuromutilin derivatives by a process known as semisynthesis, which involves chemically modifying pleuromutilin itself.
However, a large proportion of these derivatives only vary at a single position in the molecule. A practical full synthesis, which would make a wealth of additional antibiotics possible, has remained elusive.
Herzon and his team discovered an isomer of pleuromutilin, a compound that has the same connectivity, but with a different arrangement of atoms and rearrange it in the final steps of the synthesis to pleuromutilin.
Moreover, these isomers have better antibacterial properties than pleuromutilin itself, opening the door to the preparation of improved compounds.
Herzon said, making pleuromutilin is great, but we are more interested in the non-natural compounds we can access through synthesis.
More information: [Science]
Towards automation of chemical process route selection based on data mining
Towards automation of chemical process route selection based on data mining
A methodology for chemical routes development and evaluation on the basis of data-mining is presented. A section of the Reaxys database was converted into a network, which was used to plan hypothetical synthesis routes to convert a bio-waste feedstock, limonene, to a bulk intermediate, benzoic acid. The route evaluation considered process conditions and used multiple indicators, including exergy,
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Towards automation of chemical process route selection based on data mining
Towards automation of chemical process route selection based on data mining
A methodology for chemical routes development and evaluation on the basis of data-mining is presented. A section of the Reaxys database was converted into a network, which was used to plan hypothetical synthesis routes to convert a bio-waste feedstock, limonene, to a bulk intermediate, benzoic acid. The route evaluation considered process conditions and used multiple indicators, including exergy,
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