Sox9 Determines Translational Capacity During Early Chondrogenic Differentiation of ATDC5 Cells by Regulating Expression of Ribosome Biogenesis Factors and Ribosomal Proteins. Caron et al, Front Cell Dev Biol. 2021; 9: 686096.
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Sox9 Determines Translational Capacity During Early Chondrogenic Differentiation of ATDC5 Cells by Regulating Expression of Ribosome Biogenesis Factors and Ribosomal Proteins. Caron et al, Front Cell Dev Biol. 2021; 9: 686096.
Human articular cartilage defects can be treated with nasal septum cells
Human articular cartilage defects can be treated with nasal septum cells
A report from collaborating research teams from the University and the University Hospital of Basel specifies that cells isolated from the nasal septum cartilage can adapt to the environment the knee and repair articular cartilage defects. The ability of nasal cartilage cells to self-renew and adapt to the joint environment is associated with the expression of genes know as HOX genes. This…
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Mesenchymal Stem Cells Repair Cartilage Defects in Cynomolgus Monkeys
Mesenchymal Stem Cells Repair Cartilage Defects in Cynomolgus Monkeys
Repairing cartilage defects in the knee represents one of the primary goals of orthopedic regenerative medicine. Cartilage that covers the joints, otherwise known as articular cartilage, has a limited capacity for repair, which leads to further degeneration of the cartilage when it is damaged if it remains untreated. A number of surgical options for treating cartilage defects include…
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Cartilage Production From Fat-Based Stem Cells Without Exogenous Growth Factors
Cartilage Production From Fat-Based Stem Cells Without Exogenous Growth Factors
Making cartilage from fat-based stem cells would be so much more attractive if we didn’t have to use exogenous sources of growth factors. Nevertheless, fat-based stem cells remain quite attractive as a source of cartilage since these cells can be grown in culture to large numbers and can also be readily differentiated into chondrocytes if they are stimulated with the growth factor transforming…
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