I've not vanished! Well I have but not for no reason, just lacking in spoons.
Titles of some papers I'll be summarising in the near-ish future:
Hypermobility in patients with functional seizures: Toward a pathobiological understanding of complex conditions
The Postural Tachycardia Syndrome (PoTS) Bladder-Urodynamic Findings
Neurobiology of fibromyalgia and chronic widespread pain
Breathlessness and dysfunctional breathing in patients with postural orthostatic tachycardia syndrome (POTS): The impact of a physiotherapy intervention
Gender dysphoria in adolescents with Ehlers–Danlos syndrome
Other update: silly past me decided to restrict things to physical disability but I have no idea why I did that. You are welcome to send in anything not physical as well.
Speaking of sending things in, feel free to reblog or comment on this post with suggestions of papers to summarise! I'll work faster if something's staring me in the face. You can still send in asks, those will always be on unless something catastrophic happens!
The landscape of drug discovery is evolving rapidly, driven by the need for innovative solutions to tackle complex diseases. Traditional R&D models, characterized by internal research silos, have increasingly shown limitations in addressing the complexities of modern biomedical challenges.
The future, it seems, lies not in isolated efforts but in co-creation, where collaboration and the sharing of expertise become the foundation for scientific breakthroughs. In this article Dr. Tidona shares the three reasons why a unique open innovation platform approach is radically reshaping the concept of research in the pharma industry.
Breaking Down Silos: Why Co-Creation is Crucial
In today’s biomedical research landscape, the challenges are not just scientific but also organizational. Drug discovery and development are inherently risky, time-consuming, and resource intensive. To accelerate the process, the industry needs to move beyond traditional boundaries. Co-creation — bringing together experts from diverse fields to work on shared goals — has become a promising model. It leverages collective expertise, fosters creativity, and drives innovation faster than any single entity could achieve alone.
By bringing together experts in fields like oncology, immunology, neuroscience, platform technologies, and artificial intelligence, BioMed X enables its partners to harness the power of diverse perspectives.
A New Approach to Innovation: Externalizing High-Risk Research
Drug discovery often involves exploring uncharted scientific territory, where the risk of failure is high. For pharmaceutical companies, this can be a daunting and costly endeavor. By collaborating with BioMed X, these companies can externalize high-risk exploratory projects, freeing them to focus on their core strengths while tapping into the expertise and creativity of international research talents.
The model allows partners to work with BioMed X from the concept phase through to the final deliverables. Importantly, partners retain all rights in the research and development results, ensuring a seamless integration of discoveries into their pipelines. This approach is not about relinquishing control; it’s about de-risking the process while maintaining strategic oversight.
The BioMed X Career Space: Access to Global Talent
A critical component of BioMed X’s success is its Career Space, a platform that attracts talented scientists from around the world. Through competitive selection, early-career researchers relocate to the BioMed X labs in Heidelberg, Germany, or New Haven, Connecticut, where they join multidisciplinary teams focused on addressing specific scientific challenges.This relocation is more than just a change of scenery; it’s an immersion into an ecosystem designed for creativity and innovation. Unlike traditional research setups where scientists work in isolation, BioMed X brings together experts from various fields to work side by side in an open lab environment. This setup is designed to stimulate creativity and promote serendipitous discoveries that arise from the intersection of different scientific perspectives.
All the publications resulting from BioMed X projects speak for themselves: diverse teams are more innovative, often pushing beyond the boundaries of what’s possible in biomedical research. By allowing researchers to challenge each other and test unconventional ideas, the lab becomes a breeding ground for novel solutions to complex problems in areas like cancer, psychiatric disorders, and autoimmune diseases.
The success of this model highlights a new way forward — one where the brightest minds converge to solve the world’s toughest biomedical problems. By leveraging the power of co-creation, BioMed X is not just contributing to the future of drug discovery but actively shaping it. As the industry gathers at events like the German Biotech Days, it’s clear that this collaborative approach is not just an experiment but a critical evolution in how we approach healthcare innovation.
The drug discovery landscape is evolving to tackle complex diseases. Advances in pharmaceutical news and pharma industry trends are reshaping R&D models.
I am in the lucky position to be doing a degree through an institution that gives me access to a lot of medical literature that other people can't necessarily access. I'm also fairly practised at reading said medical literature because I am doing a degree that requires at least some ability to research.
I am an astronomy student, not a medical student, but I want to do everything in my power to make at least some of this research more accessible to people with complex illnesses.
If you have come across a paywalled study or something that you just can't seem to understand, send it my way and I'll give it my best shot!
Table of Contents
General questions under the cut
Can you give medical advice?
Absolutely not. And my summaries should not be construed as a perfectly faithful interpretation of the material -- they are a guide to finding the part of the article most relevant to your own research.
Can I ask you to do research on a condition or symptom for me?
No, sorry. I don't have the energy or time to do that as much as I would love to. Send me a study or piece of literature and I will be happy to access and interpret it. If you really can't find literature on your topic, you can send a question and I'll try to find a paper on it but no guarantees.
What can I send?
You can send any medical literature you want me to try and summarise (journal articles, studies, statements, etc), suggestions for accessibility improvements, questions about things I've posted (I'll link them to the orginal post), pointing out errors. Basically anything. If I can't access or answer something, I'll let you know!
Can I send something anonymously?
Absolutely! Anonymous asks are on. Unfortunately anonymous asks don't allow you to send links so minimum information I need to find the study is title, author(s), and publication date. The name of the journal it was published in is also useful! I will put the summary in the response to the ask so if you don't want to be credited and you don't want to ask anonymously, just put that in your ask and I'll accommodate.
How is this blog organised?
I have included a link to the table of contents above. I will tag all posts with the relevant condition so they show up in the archive. Each post will have a link to a second post that includes the article figures, and, if the article is not publicly available, some way of sharing important parts of it.
Are there restrictions on what disabilities/chronic illnesses the material can relate to?
I am going to loosely restrict this to conditions that have a physical component but of course if the study is on a link between a physical and other disability, that is perfectly fair game. Obviously I am more knowledgeable about the disabilities and chronic illnesses I personally experience (including POTS, hEDS, ME/CFS, and fibromyalgia) but if you send me something that I don't have experience with, I will give that caveat and do my best.
Edit: I'm actually happy to do non-physical conditions too! Why'd you restrict it, silly past me?
What language(s) can I send things in?
The language of the study must be English. If you come across something in French, I can do my best with that as well since I grew up biligual; however, all my medical treatment has been in English as is the degree I'm pursuing so I am much more comfortable with English language papers. If you want to send your question in French, go ahead but I will respond in English.
Can I help?
Yes! Of course! Just let me know how you want to help. One thing I absolutely need help with is image descriptions. I likely won't be including them unless I'm having a really good day since they're absolutely exhausting for me to write, so if you send me an image description for a figure, I will be adding it to the post immediately and crediting you if you want!!!
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The causes of inaccordant skin diseases like birthmarks, eczema, psoriasis and warts are also seen gangplank small fry nowadays in order to a very great domain. If that is the case, then paediatrics dermatologists are the best people versus settle preliminaries the dove. <\p>
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These dermatologists are mainly physicians, who should completed both a paediatrics abiding as well as dermatology occupancy. They are express an opinion unto deal with lots of entangled diseases like genodermatoses, skin diseases fusil the neonates. <\p>
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The paediatric dermatologist mainline Philadelphiaserves the problems as for acne, overthrowal of moles, basal cell, melanoma, scabies cancer, sun damage, eczema, psoriasis and the ringworm along near Botox and other chemical peels. The patients get full care and they mix contemporary practice of dermatology along with the slab care. <\p>
These dermatologists are the true leaders at the area of cosmetic surgery. Several of them have attained the preliminary step by format applicability in respect to Botox fillers and the laser cryosurgery. Handy of they robotlike perform cosmetic procedures like facelifts, Blepharoplasty and liposuction. <\p>
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