#disease variants

[larryhbernsteinme]

Complex rearrangements and oncogene amplification revealed by long-read DNA and RNA sequencing of a breast cancer cell line

Complex rearrangements and oncogene amplification revealed by long-read DNA and RNA sequencing of a breast cancer cell line

Complex rearrangements and oncogene amplification revealed by long-read DNA and RNA sequencing of a breast cancer cell line

Reporter: Stephen J. Williams, PhD

In a Genome Research report by Marie Nattestad et al. [1], the SK-BR-3 breast cancer cell line was sequenced using a long read single molecule sequencing protocol in order to develop one of the most detailed maps of structural variations in…

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[larryhbernsteinme]

Bioinformatics Tool Review: Genome Variant Analysis Tools

Bioinformatics Tool Review: Genome Variant Analysis Tools

Bioinformatics Tool Review: Genome Variant Analysis Tools

  Curator: Stephen J. Williams, Ph.D.

The following post will be an ongoing curation of reviews of gene variant bioinformatic software.

  The Ensembl Variant Effect Predictor.

McLaren W, Gil L, Hunt SE, Riat HS, Ritchie GR, Thormann A, Flicek P, Cunningham F.

Genome Biol. 2016 Jun 6;17(1):122. doi: 10.1186/s13059-016-0974-4.

Author…

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[larryhbernsteinme]

Social behavior traits embedded in gene expression

Social behavior traits embedded in gene expression

Larry H. Bernstein, MD, FCAP, Reviewer and Curator

Leaders in Pharmaceutical Intelligence

Social behavior traits embedded in gene expression

http://pharmaceuticalintelligence.com/9/29/2014/larryhbern/Social-behavior-traits-embedded-in-gene-expression

This article is a special piece on the anniversary of my brother’s death. It is special in the unique discoveries on social interaction and genetic…

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