#dna design

[gojira-ekkusu]

G2 Monster King Upgrade Kit for Transformers: Legacy Evolution Leader Class G2 Universe Grimlock by DNA Design

[gojira-ekkusu]

G2 Monster King Upgrade Kit for Age of the Primes Leader Class G2 Universe Grimlock by DNA Design

[pocoslip]

I can't believe Studio Series 86 Megatron did not have his Energon Mace

(It is Movie Accurate but Optimus Prime Never used an Axe in the 1986 Movie and yet he still has one anyway)

[roodypatooti]

"how do you feel about going on the offensive?"

:)

[aeonmagnus]

We have a special treat for Transformers Animated fans this morning. Via their Facebook page, 3rd party company DNA Design has brought to life a concept that sadly never happened back in the day – Powermaster armor for Legacy United Voyager Animated Optimus Prime! This was something that was planned for the original toyline had it continued, and while there had been plans from various 3rd party companies over the years to make it, none had come to fruition – until now, as the DK-54 upgrade kit.

“🌟 Introducing DNA Design’s DK-54 ANIMATED OP UPGRADE KITS! 🌟 🚀 Scheduled Release Date: September 2024 🚀 📅 Pre-order Deadline: May 10, 2024 📅 We are proud to present our latest masterpiece, the DK-54 meticulously crafted by DNA Design. This model brings to life the fire truck imagery from the ANIMATED original art book, making it a stunning addition to any collector’s display cabinet. As gamers, we understand the fear of regret, especially after 16 years, spanning from 2008 to the present day. We spare no effort in striving to meet everyone’s expectations. Regarding the ANIMATED OP, we have set several design directions: 🚨For the ANIMATED OP, we’ve outlined several design directions: 🚨 1.Bringing the fire truck from the animation into three-dimensional form. 2.Allowing the shoulder cannon to transform into handheld dual guns. 3.Converting the ladder into a cannon. 4.Fully integrating the hammer into the vehicle’s model. We aim for this upgrade series to cater to the preferences of all professional collectors, making your collection truly one-of-a-kind! At DNA Design, we’ve innovated a unique weapon storage system to complement this masterpiece, designed to captivate the heart of every collector. Stay tuned for more updates and details on this extraordinary release! Thank you for your support! 🙌”

[aoiheyaus]

DNA Design DK-16 Gear Master Upgrade Kit for SS-49/61/08 Bumblebee, Sentinel Prime & Blackout

DNA Design DK-16 Gear Master Upgrade Kit for SS-49/61/08 Bumblebee, Sentinel Prime & Blackout! Invincible and exquisite workmanship, made of high-quality materials with multiple joints movable, vivid image, fine workmanship, and the gameplay is also very interesting, making people addicted to it

[scifigeneration]

DNA design that anyone can do

Researchers at MIT and Arizona State University have designed a computer program that allows users to translate any free-form drawing into a two-dimensional, nanoscale structure made of DNA.

Until now, designing such structures has required technical expertise that puts the process out of reach of most people. Using the new program, anyone can create a DNA nanostructure of any shape, for applications in cell biology, photonics, and quantum sensing and computing, among many others.

"What this work does is allow anyone to draw literally any 2-D shape and convert it into DNA origami automatically," says Mark Bathe, an associate professor of biological engineering at MIT and the senior author of the study.

The researchers published their findings in the Jan. 4 issue of Science Advances, and the program, called PERDIX, is available online. The lead authors of the paper are Hyungmin Jun, an MIT postdoc, and Fei Zhang, an assistant research professor at Arizona State University. Other authors are MIT research associate Tyson Shepherd, recent MIT PhD recipient Sakul Ratanalert, ASU assistant research scientist Xiaodong Qi, and ASU professor Hao Yan.

Automated design

DNA origami, the science of folding DNA into tiny structures, originated in the early 1980s, when Ned Seeman of New York University proposed taking advantage of DNA's base-pairing abilities to create arbitrary molecular arrangements. In 2006, Paul Rothemund of Caltech created the first scaffolded, two-dimensional DNA structures, by weaving a long single strand of DNA (the scaffold) through the shape such that DNA strands known as "staples" would hybridize to it to help the overall structure maintain its shape.

Others later used a similar approach to create complex three-dimensional DNA structures. However, all of these efforts required complicated manual design to route the scaffold through the entire structure and to generate the sequences of the staple strands. In 2016, Bathe and his colleagues developed a way to automate the process of generating a 3-D polyhedral DNA structure, and in this new study, they set out to automate the design of arbitrary 2-D DNA structures.

To achieve that, they developed a new mathematical approach to the process of routing the single-stranded scaffold through the entire structure to form the correct shape. The resulting computer program can take any free-form drawing and translate it into the DNA sequence to create that shape and into the sequences for the staple strands.

The shape can be sketched in any computer drawing program and then converted into a computer-aided design (CAD) file, which is fed into the DNA design program. "Once you have that file, everything's automatic, much like printing, but here the ink is DNA," Bathe says.

After the sequences are generated, the user can order them to easily fabricate the specified shape. In this paper, the researchers created shapes in which all of the edges consist of two duplexes of DNA, but they also have a working program that can utilize six duplexes per edge, which are more rigid. The corresponding software tool for 3-D polyhedra, called TALOS, is available online and will be published soon in the journal ACS Nano. The shapes, which range from 10 to 100 nanometers in size, can remain stable for weeks or months, suspended in a buffer solution.

"The fact that we can design and fabricate these in a very simple way helps to solve a major bottleneck in our field," Bathe says. "Now the field can transition toward much broader groups of people in industry and academia being able to functionalize DNA structures and deploy them for diverse applications."

Nanoscale patterns

Because the researchers have such precise control over the structure of the synthetic DNA particles, they can attach a variety of other molecules at specific locations. This could be useful for templating antigens in nanoscale patterns to shed light on how immune cells recognize and are activated by specific arrangements of antigens found on viruses and bacteria.

"How nanoscale patterns of antigens are recognized by immune cells is a very poorly understood area of immunology," Bathe says. "Attaching antigens to structured DNA surfaces to display them in organized patterns is a powerful way to probe that biology."

Another key application is designing light-harvesting circuits that mimic the photosynthetic complexes found in plants. To achieve that, the researchers are attaching light-sensitive dyes known as chromophores to DNA scaffolds. In addition to harvesting light, such circuits could also be used to perform quantum sensing and rudimentary computations. If successful, these would be the first quantum computing circuits that can operate at room temperature, Bathe says.

[allspark]

Site sponsor TFSource has listed an August preorder with gallery for DNA Design’s extensive upgrade kit for the massive Studio Series monster Grimlock. The kit includes new articulated hands and a left arm, new weapons, and enhancements for the mighty Dinobot knight’s dinosaur form.

While DNA Design have released complete figures of their own based on Transformers characters, they have also produced upgrade kits for official figures, such as the Titans Devastator, Fortress Maximus, and Metroplex, improving articulation and filling in the gaps, literally and figuratively, where the mass-market toy could not. The Grimlock kit brings Studio Series Grimlock just that much closer to the film version seen in Age of Extinction.

The kit is listed at $29.99 USD. Check out the preorder at TFSource for more details.

Discuss Transformers: Studio Series on the Allspark Forums in our Studio Series thread, and check in at B.O.T. Talk for this and other upgrade kits and unofficial figures. You can also join our Discord server for realtime chat.

DNA Design Studio Series Grimlock Upgrade Kit Preorder on TFSource Site sponsor TFSource has listed an August preorder with gallery for DNA Design's extensive upgrade kit for the massive Studio Series monster Grimlock.