Jan 25
Reversible Metal Coordination Switch Enables Activatable Sonodynamic Therapy via Dual-Death and Immune Synergy - Research
Sonodynamic therapy (SDT) holds great potential for disease treatment, yet its efficacy is limited by constitutive reactive oxygen species (ROS) generation and poor selectivity. Herein, we report a generalizable strategy using reversible metal-ion coordination to regulate the sonodynamic activity of semiconducting polymers (SPs). A diketopyrrolopyrrole (DPP)-based polymer (SPC) serves as the…
#Activatable#Coordination#doi:10.1002/adma.202521565#DualDeath#Enables#Fei Li#Huayu Tian#Immune#MEDLINE#metal#National Center for Biotechnology Information#National Institutes of Health#National Library of Medicine#NCBI#NIH#NLM#pmid:41580916#PubMed Abstract#research#reversible#Sonodynamic#switch#Synergy#therapy#Zihui Liu