The Use of Flolan in the Treatment of Pulmonary Hypertension
Learn how Flolan (epoprostenol) helps treat pulmonary arterial hypertension (PAH) by relaxing blood vessels, improving blood flow, and reducing heart strain in patients with advanced disease.
Flolan, generically known as epoprostenol, is a prescription medication used in the treatment of pulmonary arterial hypertension (PAH) a serious condition where high blood pressure in the lungs makes it difficult for the heart to pump blood effectively.
Administered as a continuous intravenous infusion through a catheter and portable pump, Flolan works by relaxing and widening the blood vessels in the lungs, which improves blood flow and reduces the workload on the heart. This vasodilatory effect also helps prevent platelets from clumping, supporting smoother circulation. Because PAH limits exercise capacity and causes significant symptoms, Flolan can help enhance patients’ ability to be more active and potentially improve long‑term outcomes.
Treatment requires careful medical supervision, dedicated catheter care, and adherence to dosing protocols due to the complexity of infusion therapy and risk of side effects such as dizziness, headache, flushing, and bleeding.
👉 Learn more about Flolan and PAH treatment here