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i personally think that if i have a gene variant of unknown significance they should not tell me about it
like that's so fucked up lmao "this part of your body is built extra wrong and it may or may not kill you someday lol"
anyway that was a fun geneticist appointment. anybody else have gene variants for thoracic aortic aneurysms/dissections? i feel like i have a ticking time bomb in my chest lmao fuck
MS Researchers Focus on Mechanism of HLA-DR15 Gene Variant
Based in Southern California, Stephanie Zargar is an office manager with Cal-Am Properties and manages a full range of operational activities. One area in which Stephanie Zargar has a strong personal interest is multiple sclerosis research, which addresses a disease that reflects complex interactions between environmental and genetic factors. Recent research at the University Hospital Zurich focuses on HLA-DR15, a gene variant that carries 60 percent of the genetic risk of the disease. The study reveals the mechanism by which immune cells of those with HLA-DR15 genetic variants are primed to recognize microbes like the Epstein-Barr virus effectively. Unfortunately, this can lead to an immune reaction occurring against the individual’s own brain tissue. The reaction centers on the T lymphocytes, which are tasked with modulating the immune response and distinguishing between the body's own tissue and foreign proteins. Through a process of cross-reactivity, they can erroneously attack proteins in the brain. The researchers are working to understand the exact mechanism through which this occurs, which may ultimately lead to addressing a number of autoimmune conditions.
Most of the genetic risk for autism comes from versions of genes that are common in the population rather than from rare variants or spontaneous glitches.
A common genetic variant that affects one in three people significantly increases the risk of colorectal cancer from the consumption of red meat and processed meat.
