#h&e

[thatmohstech]

Basal cell carcinoma with H&E and toluidine blue

[bpod-bpod]

Top to Bottom

Ever tried talking while doing a handstand? It's tricky. Your body works best the right way up. Just like cells in your body do. Cell shape, structure and how components inside cells are organised help them figure out their orientation – this is called cell polarity. Disrupted cell polarity can cause cancer and other diseases, including gut disorders. Cells lining your intestine are 'polarised' – with one side facing the gut tube interior (apical), the other the blood stream (basal) – along an apicobasal axis. In mice, RNA and proteins in these cells are asymmetrically spread along this axis. Researchers investigate if this happens in humans using laser-capture microdissection to isolate top and bottom segments from intestinal epithelial cells (pictured using H&E staining). Analysing the location of genes actively making proteins in these segments revealed that RNA and proteins are asymmetrically spread along this axis. This research provides a way to better understand the biology of the human intestine.

Written by Lux Fatimathas

Image from work by Roy Novoselsky and colleagues

Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel

Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in PLOS Biology, December 2024

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[histopics]

An artery (top) adjacent to skeletal muscle. The skeletal muscle fibers and smooth muscle within the wall of the artery both stain strongly with eosin.

[bbcphile]

i've been rereading harboured & encompassed for the fourth-or-so time and i JUST clocked the "very possibly, but i thought you could use the company" in chapter 8 i swear to god.....

Lol! It makes me so happy when people pick up on the direct quotations from the show that I sprinkled throughout the fic! Thanks!

Also, OMG, you’ve read it four times??!! I’m so honored!! Thank you!

[the-art-of-medicine]

White Blood Cells

Identifying WBCs via H&E (Haemotoxylin and Eosin) staining

Monocyte - Kidney shaped nucleus

Basophil - Bi-lobed nucleus, dark purple cytoplasmic granules

Lymphocyte - Large spherical nucleus

Eosinophil -  Bi-lobed nucleus, red cytoplasmic granules

Neutrophil - Multi-lobed nucleus, faint red granules

[madamsecretaryprompts]

"I'm so sorry. Can you forgive me?" "I'll forgive you - wait, what did you do?"

[gilmarverdes]

poppies | heartbreaks and earthquakes, part 3

fandom: shadowhunters

rel: raphael & magnus

warning: this describes raphael’s torture in some detail, be careful 

summary: 

He prepares for his meeting with Victor Aldertree with precise care, spends two hours in front of his mirror, buried in his wardrobe. No matter what happens, look untouchable. Be calm. This will pass. Magnus always said that there is light in the darkness. His hands shake as he buttons his suit, but he maintains his composure well; at this point, every fear that Raphael feels, he feels minimally. His mind always empty, his mind always full, his body always stressed, his brain always running over every possible outcome. Be calm. This will pass.

READ ON AO3: http://archiveofourown.org/works/9453164