#hemorrhage

[mav-the-artist]

Hemorrhage doodle :]

(Hemo belongs to @beemers-hell)

[velvetjester]

I'm losing blood right now but it's at the hospital and the doctors aren't vampires

[nightingalesandnorco]

Can you talk more about hemorrhaging and blood loss?

Hemorrhage is defined as a loss of 15% or more of the total blood volume. An adult human body generally has between 4500 and 5500 mL of blood. People can usually lose up to 14% of their blood volume (between 630 and 770 mL [1.3 to 1.6 pints] depending on the total volume) without experiencing symptoms. After 15% (Class I), hemorrhage is divided into three classes:

Class II: 15% to 30%

Class III: 30% to 40%

Class IV: more than 40%

Hemorrhage can be external or internal. Internal hemorrhage may manifest with blood in the vomit, urine, or stool or there may be no visible blood.

Hypovolemic shock, or shock caused by too little circulating blood, can occur at any point in the hemorrhage and is divided into three degrees:

Mild (15% to 25%): characterized by sweating, weakness, fast heart rate, and a slight fall in blood pressure

Moderate (25% to 35%): characterized by pallor, restlessness, reduced urine output, and a moderate fall in blood pressure

Severe (35% to 50%): characterized by a significant fall in blood pressure, agitation, confusion, and no urine output

Hemorrhage is treated by controlling the source of bleeding, if possible, and initiating fluid resuscitation with saline or lactated ringer solution through large bore IVs. Blood and blood product transfusions are also indicated when there has been a significant loss of blood components such as red blood cells. Oxygen is also administered, as oxygen saturation tends to drop as the body loses more red blood cells.

If there's anything specific you want to know, send me another ask!

Happy whumping!

[selenophile-ib]

Hemorrhage

[glkr-xx]

Don't fall away, and leave me to myself

Don't fall away, and leave love bleeding in my hands

In my hands again

[anarboreo]

She an on my emia till I uhhhh I forgot where I was going with this

girlie your bloods carrying the wrong stuff, shemoglobin never fails to deliver 💅

[justkidneying]

ANOTHER regen question!

Let's see if I phrase this one right it's been rolling in my brain a bit

Assumptions are the character heals a slower than Wolverine and they've just suffered some serious blood loss. Like they lost ~3L of it and the wound has now closed up and the body's working to create as much blood as possible.

Given how bone marrow is where blood comes from, what sorts of things might they have to deal with in the recovery period? Like, as the body is taxing the marrow like that (and/or whatever else it has to)?

I'm going to assume this is a ~200lb man, just to give some leeway. So a big guy like this would have maybe 6 liters of blood in him (most humans range from 4-6 L). If he loses ~3 L, I would say he would probably just die. If blood loss is >40%, that's a Class IV hemorrhage, which presents with absent peripheral pulses, hypotension (low blood pressure), and no peepee output. This person will go into hemorrhagic shock. Since they lack the oxygen-carrying hemoglobin that is found in blood, they will not be able to supply oxygen to their tissues. This stops the usually metabolic processes and switches the body to anaerobic metabolism, which makes lactic acid and very little ATP (energy). Lactic acid leads to acidosis. Acidosis leads to cell death, coma, and plain ole death. He will die.

But wait! He's got regenetative powers to save him, right? No. If his powers aren't magical, then he will still die. Because regeneration is based on being able to replicate cells very quickly, he would need to do it fast enough to beat the cells that are dying. Unfortunately, he doesn't have enough ATP to do normal cell stuff and make a bunch more. Replication of cells requires a lot of ATP (energy). So he will still die.

Now, let me answer the second question, and we will go back to when he is still alive. Let's change it so he only lost ~30% of his blood volume (1.8L). He's still not doing good (he has Class III hemorrhage) but he can live. This will present with pallor, coolness in the limbs, altered mental status, narrowing blood pressure (the top and bottom numbers are getting close together), increased respiratory rate, and increased heart rate. The body is trying to keep blood flow to the vital organs. Let's say he survives and now he's home and trying to recover.

Blood has a lot of things in it, but the important bits are plasma (the liquid bit which makes up ~55% of blood), red blood cells (they carry oxygen), platelets (for clotting) and white blood cells (part of the immune system).

The most important one here are the RBCs. 90% of plasma is water, and you won't die right away without the other ones. The body measures RBCs through the kidney. If the kidney sees that you don't have enough of them, then it sends a hormone (EPO) to the spongey inner bone where blood is made. EPO causes more stem cells to turn into RBCs (instead of WBCs or platelets). To make these, you need iron. The iron stores of the body will be used, and you will take up more iron from your food.

Overall, I'd say the guy will feel like shit, and he should probably take a break for about 3 months while he replinishes his blood supply. He should eat foods high in iron, maybe take an iron supplement. But he'll be anemic while he recovers and be low on those other blood cells. Honestly, his regen powers aren't that useful here. They were useful in fixing whatever caused the blood loss, keeping him from losing a ton of cells to blood supply issues, and that's about it. If he doesn't have an advanced factor, then he can't really be helped with making more RBCs.

I hope I answered your question, and thank you very much for asking it!

[90s-2000s-barbie]

Fuel - Hemorrhage (In My Hands) [2000]