#humanresearch

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IMMORTALITY CURE //--002X - grazdgfx

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Lab08_SEC41

[thetravelingtotoros]

This is the Belmont Report, a series of rules about the ethical treatment of individuals in research situations. Basically, if it sounds bad it probably is as you shouldn't be doing it #totoro #belmontreport #ethical #standards #humanresearch #totoro (at NCERC)

[biochick37]

All ready to go for the afternoon! ...of course then we're unable to get the full set of samples from one patient and the other cancelled. #humanresearch

[nasa]

4 people are living in an isolated habitat for 30 days. Why? Science!

This 30 day mission will help our researchers learn how isolation and close quarters affect individual and group behavior. This study at our Johnson Space Center prepares us for long duration space missions, like a trip to an asteroid or even to Mars.

The Human Research Exploration Analog (HERA) that the crew members will be living in is one compact, science-making house. But unlike in a normal house, these inhabitants won't go outside for 30 days. Their communication with the rest of planet Earth will also be very limited, and they won’t have any access to internet. So no checking social media kids!

The only people they will talk with regularly are mission control and each other.

The crew member selection process is based on a number of criteria, including the same criteria for astronaut selection.

What will they be doing?

Because this mission simulates a 715-day journey to a Near-Earth asteroid, the four crew members will complete activities similar to what would happen during an outbound transit, on location at the asteroid, and the return transit phases of a mission (just in a bit of an accelerated timeframe). This simulation means that even when communicating with mission control, there will be a delay on all communications ranging from 1 to 10 minutes each way. The crew will also perform virtual spacewalk missions once they reach their destination, where they will inspect the asteroid and collect samples from it. 

A few other details:

The crew follows a timeline that is similar to one used for the ISS crew.

They work 16 hours a day, Monday through Friday. This includes time for daily planning, conferences, meals and exercises.  

They will be growing and taking care of plants and brine shrimp, which they will analyze and document.

But beware! While we do all we can to avoid crises during missions, crews need to be able to respond in the event of an emergency. The HERA crew will conduct a couple of emergency scenario simulations, including one that will require them to maneuver through a debris field during the Earth-bound phase of the mission. 

Throughout the mission, researchers will gather information about cohabitation, teamwork, team cohesion, mood, performance and overall well-being. The crew members will be tracked by numerous devices that each capture different types of data.

Past HERA crew members wore a sensor that recorded heart rate, distance, motion and sound intensity. When crew members were working together, the sensor would also record their proximity as well, helping investigators learn about team cohesion.

Researchers also learned about how crew members react to stress by recording and analyzing verbal interactions and by analyzing “markers” in blood and saliva samples.

In total, this mission will include 19 individual investigations across key human research elements. From psychological to physiological experiments, the crew members will help prepare us for future missions.

UPDATE:

Mission success! After a simulated mission to an asteroid, the crew “splashed down” around 10:30 p.m. EST on Wednesday, Feb. 24 and exited the habitat for the first time in 30 days.

Want a full, 360 degree look at HERA? Check out and explore the inside of the habitat.

Make sure to follow us on Tumblr for your regular dose of space: http://nasa.tumblr.com

[mentorhealth]

Assessing Risk in Human Research Protocols

Overview: 45 CFR 46.111 (a)(2) states, "In evaluating risks and benefits, the IRB should consider only those risks and benefits that may result from the research (as distinguished from risks and benefits of therapies subjects would receive even if not participating in the research)." How the study is designed can minimize potential risks to participants. Studies that are deemed "minimal risk" have greater options when it comes to using an expedited review system and options for consent.

Risk rating also affects how elaborate a data safety monitoring plan will be required and measures put in place to protect privacy for the individuals and confidentiality of the data. The more that is done to reduce or minimize potential risks to research participants, the fewer regulatory requirements there are reducing burdens on the researchers and their teams. Attending this webinar will give you insight into research studies are assigned a risk rating, what that risk rating means, and what you can do to minimize risks to participants.

Read more: http://www.mentorhealth.com/control/w_product/~product_id=800532LIVE/

[abitlikealice]

"Project MKULTRA, or MK-ULTRA, was the code name for a covert, illegal CIA human research program, run by the Office of Scientific Intelligence. This official U.S. government program began in the early 1950s, continuing at least through the late 1960s, and it used U.S. and Canadian citizens as its test subjects."

Further reading: http://en.wikipedia.org/wiki/Project_MKULTRA