It's something that's talked about a lot, but it's constantly on my mind, okay? ('3')
The Whole Cake Island arc with Sanji's brothers, the normal Vinsmokes, up to Judge. Like, Judge was an idiot who wanted his kids to be strong and all, but he didn't experiment on them, he just made them more competitive and stuff.
12&3 are still idiots and bother Sanji, but more like older brothers (and Yonji) bothering their younger brother. They wouldn't call it a mistake and all that, they would simply tell him this joke that the brothers make.
Ichiji: We found you in a garbage dump when you were a baby.
Niji: We found you in the trash too.
Reiju, looking at her brothers, knowing that she used to say the same thing to Ichiji when he was a child: !!!