The last remaining female Winchester was in the middle of doing something she had seemingly been doing her entire life. Running. She was running for her life. Her brothers and her were working what was suppose to be a standard "ghost" hunt when they had been ambushed by demons. The whole thing was most likely a trap. She had been the only one of the three to escape, and she was completely consumed with panic from that fact. Sam had told her to get out. Run.
Since then she'd been praying, no, mentally screaming for her other brother and fellow angel, Castiel. She'd gotten no response. No familiar shuffle of wings, no sudden confused and worried expression to comfort her. Nothing. She was on her own now. She continued to run, while at the same time desperately trying to think of a way to save her brothers. Even though she was an angel, she was by far one of the most powerful. Over twenty years living as a human had done that to her. She felt pathetic. How could she have left them...? Tears began to sting her eyes as she continued running, seeking out shelter. Eventually she just ran into a dark alley, which she knew probably wasn't the best idea. She just needed some time to think. She leaned against the cool wall, panting as she tried to catch her breath, and tried to think of some way to get them out of this.