#ipsc clinical study

[pknoepfl]

Takahashi team IPS cell vision paper marks major stem cell milestone

Takahashi team IPS cell vision paper marks major stem cell milestone

Ring the bell for a stem cell milestone.

There’s been a whole lot of commotion about the NEJM article yesterdaydocumenting the experiences of three women with macular degeneration who were blinded by non-FDA approved stem cell eye injections of fat stem cells at a business in Florida, but in the same issue of the journal there also was some encouraging stem cell news that came in the form of…

View On WordPress

[pknoepfl]

Nominations open for Stem Cell Person of the Year 2016 Award

Nominations open for Stem Cell Person of the Year 2016 Award

Nominations are open starting today for the Stem Cell Person of the Year Award for 2016. Please email me your nominations: knoepflerATucdavisDOTedu.

This is a unique award as it is given to an individual who has taken risks to help others within the stem cell field and they based their actions on outside-the-box thinking.

Another unusual aspect is that anyone is eligible for the prize whether you…

View On WordPress

[pknoepfl]

Good stem cell news as Takahashi IPS Cell Trial to Resume

Good stem cell news as Takahashi IPS Cell Trial to Resume

Some good news today as the pioneering induced pluripotent stem (IPS) cell trial led by Dr. Masayo Takahashi will resume.

This clinical study with a focus on macular degeneration has been on hold for quite some time due to regulatory changes in Japan. There had also been concerns over mutations in the 2nd patient’s IPS cell product.

As previous signs had indicated, the new clinical work will have…

View On WordPress

[pknoepfl]

Historic turning point for IPS cell field in Japan?

Historic turning point for IPS cell field in Japan?

As many of you know, the pioneering, first of its kind IPSC clinical study in Japan has been suspended as I first blogged about here. 

In the comments section of that blog post there has been a helpful overall discussion that has involved Dr. Masayo Takahashi, the leader of the trial. It is great that Dr. Takahashi has been participating in this discussion and I commend her for that openness.

Thi…

View On WordPress

[pknoepfl]

Landmark IPSC clinical study on hold due to genomic issue

Landmark IPSC clinical study on hold due to genomic issue

The pioneering induced pluripotent stem cell (IPSC) clinical study in Japan led by pioneering stem cell clinical researcher Dr. Masayo Takahashi has been stopped reports the WSJ in Japan. This development is confirmed by other sources and in a PDF report by RIKEN (in Japanese here).

One patient was transplanted in September 2014 with their own IPSC-derived retinal pigment epithelial cells (using…

View On WordPress

[pknoepfl]

Stem Cell Person of the Year 2014: Masayo Takahashi

Stem Cell Person of the Year 2014: Masayo Takahashi

Dr. Masayo Takahashi,  Asahi photo

Congratulations to Masayo Takahashi, MD, PhD, the winner of the 2014 Stem Cell Person of the Year Award.

Dr. Takahashi received this award including the $2,000 prize for her exceptional achievements in stem cell research in 2014. She was selected as the winner from a stellar group of top 12 finalists this year.

Takahashi leads a team doing high-risk, high reward…

View On WordPress

[pknoepfl]

Yamanaka Interview on Clinical Use of Pluripotent Stem Cells

Yamanaka Interview on Clinical Use of Pluripotent Stem Cells

Dr. Shinya Yamanaka.                                           Photo from CiRA, Kyoto University

I invited Nobel Laureate Shinya Yamanaka to do an interview on the future of clinical translation of induced pluripotent stem cells (iPSC).

He provides some intriguing new insights into the iPSC field and the broader stem cell arena.

PK: The Takahashi Team’s active Clinical Study using iPSCs to make…

View On WordPress