#labeling tools

[iroatech]

IROA utilizes full metabolic labeling to distinguish between two cell populations, specifically both 5% 13C (to label experimental samples) and 95% 13C (to label control samples). How is this achieved? Compounds are randomly and universally labeled to achieve this effect. The relative abundances of the isotopes of carbon are altered; i.e. enriched in one particular isotope and depleted in its other isotopic form. For example, 95% U-13C6-Glucose is not actually 95% 13C6 and 5% 12C6. In this case, each carbon atom position (1,2,3,4,5,6) has a 95% chance of being 13C labeled and a 5% chance of being 12C. Compounds such as 5% and 95% U-13C6-Glucose are produced especially for IROA Technologies LLC by Cambridge Isotope Technologies, Inc.

[iroatech]

IROA technologies LLC – Introducing advanced Isotope labeling tools for metabolomics

Clinically relevant metabolomes data needs to be reproducible. This requires accurate identification,completely reproducible quantitation, and performance criteria for instrumentation. And only the metabolic profilingtools such as Isotope labeling tools for metabolomics can help you to achieve that.