#lamivudine

[er-cryptid]

Lamivudine

Names -- Epivir -- Epivir HBV -- 3TC

Class -- antiretroviral -- nucleoside reverse transcriptase inhibitors (NRTI)

Use -- management of HIV infection in combination with other antiretrovirals -- combination prevents resistant strains from developing

Action -- inhibits the activity of HIV-1 reverse transcriptase -- this interferes with the order of transcription -- this terminates viral DNA growth

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[pozmagazine]

FDA Approves Mylan’s Cut-Price HIV Tablets Symfi Lo and Cimduo

The Food and Drug Administration (FDA) has approved two new antiretroviral (ARV) combination tablets, the single-tablet regimen Symfi Lo (efavirenz/lamivudine/tenofovir disoproxil fumarate) and the two-drug tablet Cimduo (tenofovir disoproxil fumarate/lamivudine). Mylan has indicated that the company intends to offer the tablets at a significant discount compared with the price of similar ARV treatments.

[kaylasandrra]

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[kaylasandrra]

Lamivudine

[kaylasandrra]

What is lamivudine for and how do I take it?

Lamivudine is commonly used to treat long-term hepatitis B virus infection, which can cause inflammation and damage to the liver. Lamivudine reduces the amount of hepatitis B virus in your body to limit damage to your liver. It is a tablet which should be taken by mouth; the usual dose is 100mg once a day. Lamivudine can be taken with or without food. Your doctor or liver nurse specialist may prescribe a different dose if there are problems with your kidney function.

[mollyleonaa]

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[rickvictor]

[pharmaceutical0]

Lamivudine uses & Machanism of action

Lamivudine is an antiretroviral medication used to prevent and treat HIV/AIDS.

Lamivudine may also be used as part of an antiretroviral therapy (ART) regimen to prevent mother-to-child transmission (perinatal transmission) of HIV.

Machanism of action

Lamivudine is a synthetic nucleoside analogue. Lamivudine is phosphorylated intracellularly to lamivudine triphosphate, L-TP. Incorporation of the monophosphate form into viral DNA by hepatitis B virus (HBV) polymerase results in DNA chain termination. L-TP also inhibits the RNA- and DNA-dependent DNA polymerase activities of HIV-1 reverse transcriptase (RT). L-TP is a weak inhibitor of mammalian alpha-, beta-, and gamma-DNA polymerases.

Click here to know more:- https://www.simsonpharma.com/blog-details/Lamivudine