Solving Cold Cases with Low-Quality DNA: Whole Genome Sequencing Explained #worldresearchawards
Explores how forensic investigative genetic genealogy (FIGG) can be successfully applied using low-quality, degraded, or low-coverage DNA samples through whole genome sequencing (WGS) technologies.
We discuss the scientific principles behind analyzing compromised DNA, including challenges related to low template input, sequencing noise, contamination, and data interpretation. The presentation highlights how next-generation sequencing (NGS) and advanced bioinformatics enable forensic scientists to extract usable genetic information from samples previously considered unsuitable for analysis.
Nomination Link: https://forensicscientist.org/award-nomination/?ecategory=Awards&rcategory=Awardee
Website: https://forensicscientist.org/
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