#lupeol

[locabella503]

RECEIVED MY EGGPLANT DAILY BHA TONER BY @bonajour_official FOR A TRIAL FEE OF $3.99 FROM @0.8l_usa IN EXCHANGE FOR MY REVIEW. 🍆💦🍆💦🍆💦🍆💦🍆💦🍆 Eggplant Daily BHA Toner is made the ingredient for anti-trouble skincare, LUPEOL gives you a solution to have clear and fine skin, and BHA Toner that washes away impurities, dead skin cell, and sebum (pH 5.5) 84.43% Eggplant extract which has real; 🍆 #LUPEOL - powerful as preventive & curative anti-melanoma and anti-tumour agents. Lupeol comes from the extract from the leaves of the Castanea (chestnut) tree, & has been widely used in the pharmaceutical &food supplement industries. By developing a proprietary active molecule, Lupeol the active ingredient is allowed to penetrate the skin &reach deep into the epidermis for maximum efficiency. 🍆 #BHA - stands for Beta Hydroxy Acid. The most common BHA is #SalicylicAcid, typically used for treating acne. BHAs are good for exfoliating; getting rid of dead skin & allowing new skin to grow. Correcting dark spots, photo-damage, improving the skin's texture. BHA is an oil loving acid, it’s preferred for oily, acne-prone skin for treating blackheads &whiteheads. It is likely you'll see less redness, smoother, even skin with fewer breakouts. Eggplant Daily BHA Toner sets up the pH balance of skin to initiate healthy, acne free skin. I really wanted to experience Bonajour Eggplant Daily BHA Toner; for my hyperpigmentation I have on my cheeks &for my daughters whom are getting the occasional pimple +blackheads. It has a medicinal scent, that goes away. Eggplant Daily BHA Toner does really work, my daughter was experiencing one of those nasty painful ingrown pimples. We applied Eggplant Daily BHA Toner to the area, the next day; it was smaller with no red irritation. We we’re both shooked & amazed on how fast it works on pimples. Leaving her skin clean, smooth plus pain free. This is one Toner that I will purchase again. It’s always good to have a BHA on hand. #08literusa #08L #08Lbestapril #literites #review #bonajourofficial #eggplantbhadailytoner #beautiejunkie #skincareaddicts #kbeauty #toners #dermatology #estheticians #aesthetics #locabella503 #beautiejunkieapproved

[outoftheboxscience-blog]

Male Contraception: This Plant-Based Birth Control Could Work

At this moment men have two options for contraception: the use of a condom to catch the sperm or to have a vasectomy – sterilizing operation which cut the two tubes that carry sperm to the penis from where they are made in the testicles. Condoms are not 100% reliable (failure rate of around 18%) and it is a short term solution, while a vasectomy is a permanent option and just some of men manage to successfully reverse the operation.

The most optimistic prospect is Vasalgel, which has shown to be effective in animal trials. Other seemingly promising alternatives have faced development barriers—last year, for instance, a groundbreaking study on a male contraceptive injection ended early because the participants couldn’t handle the annoying side effects, like mood swings and acne.

Contraceptive failure rates. Image credit: Centers for Disease Control and Prevention

Now, a group of researchers from the University of California – Berkeley have started testing out a new approach. They have found that two chemicals found in folk medicine can help block the fertilization of an egg and could make effective alternatives to hormone-based contraceptives.

Blocking CatSper Channels

CatSper channel known as calcium channel of sperm is vital for male fertility and it is activated by the progesterone hormone. Scientists have known about CatSper since 2001 when they stumbled across it while studying male infertility. The patients, it turned out, had a mutation in at least one of the nine genes that code for CatSper.

In this study, researchers screened more than 50 chemical compounds to find a few that could tightly bind with CatSper and block it. It turns out that the two compounds proved to be the best blockers. They found that concentrations of lupeol (a common molecule found in plants like olives, mangos, and grapes) could prevent calcium ions from giving sperm the boost it needs to penetrate an egg. The second compound is pristimerin used in traditional Chinese remedies to treat arthritis.

The female hormone progesterone (green) affects the CatSper ion channels (red) in the tail of the sperm, which then allow calcium ions (yellow) to flow into the sperm. Blocking progesterone activation could lead to a unisex birth control method. Image credit: Caesar Foundation

This study is still pre-clinical and researchers working currently on animal trial. If everything goes well, this method could lead to a unisex birth control method that works by blocking progesterone activation. For women, this could be a plan B, which would be effective before fertilization, or within six hours of sex. For men, it could work analogously to the pill.

Assistant professor of molecular and cell biology and study author Polina Lishko said that this could be a generation of emergency contraceptives which they nicknamed the molecular condoms.

#CatSperChannels, #Lupeol, #MaleContraception, #Plant-BasedBirthControl, #Pristimerin https://outoftheboxscience.com/health/sex-reproduction/male-contraception-plant-based-birth-control-work/

[madamlaydebug]

Mango Compound Kills 99% of Lung Cancer Cells: In this just-published study, researchers found that mangiferin, a natural compound found uniquely in mango fruit, was so toxic to human lung cancer cells it killed up to 99% of them in 48 hours. Incredibly, this result was very comparable to the chemo-drug cisplatin, used in the same study! The mango compound killed cancer cells by triggering their mitochondria to initiate programmed cell death. What makes mangos so powerful? They are actually rich in two unique anti-cancer compounds: lupeol and mangiferin. Beyond suppressing cancer, mangiferin has also been found to be a natural anti-bacterial, antiviral, anti-inflammatory, pain reducer, liver protector. It’s been shown to protect the brain from oxidative damage and enhance cognitive performance (in lab animals) and intriguingly it’s also a natural MAO inhibitor— meaning that it could theoretically boost adrenalin levels and improve mood. Mangos are also a great source of vitamin C, vitamin A, B vitamins, potassium and magnesium. They make a great breakfast with yogurt on top, and are delicious blended in your favourite fruit smoothie. #Mango #LungCancer #Magiferin #Lupeol http://www.ncbi.nlm.nih.gov/pubmed/26935347