#mutagenicity

[biology-geology-beaches-india]

The Scientific Research Notes Of S. Sunkavally (years; 2002-2011).

165-168.

[ralphturchiano]

Influenza A vaccination associated with 6.3 times more aerosol shedding than non vaccinated

Editors Note (Ralph Turchiano: I encourage you to review the full study as I shall link it below. I am only highlighting the two outcomes that require urgent further investigation due to the rapid mutagenicity of H3N2 . Study Quote # 1  “In adjusted models, we observed 6.3 (95% CI 1.9–21.5) times more aerosol shedding among cases with vaccination in the current and previous season compared with…

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[environmentguru]

In vitro microbiological mutagenicity studies of hydro carbon propellants

In vitro microbiological mutagenicity studies of hydro carbon propellants https://www.environmentguru.com/pages/elements/element.aspx?utm_source=dlvr.it&utm_medium=tumblr&id=5988272

[environmentguru]

Did the EPA and CDC Mislead Local and State Officials and the Public on Safety of Mosquito Pesticides Used to Fight Zika Virus?

var icx_publication_id = 18566; var icx_content_id = '1064039'; Click here for reuse options! Naled, an insecticide being used in community mosquito spraying in the U.S., was banned by the EU in 2012 due to "unacceptable risk." Beyond http://www.environmentguru.com/pages/elements/element.aspx?utm_source=dlvr.it&utm_medium=tumblr&id=3993625

[environmentguru]

Investigating a relationship between the mutagenicity of arylboronic acids and 11B NMR chemical shifts

Chemical Research in Toxicology, Volume 0, Issue ja, -Not available-. http://dlvr.it/B1h4VV

[environmentguru]

Novel Nitro-PAH Formation from Heterogeneous Reactions of PAHs with NO2, NO3/N2O5, and OH Radicals: Prediction, Laboratory Studies, and Mutagenicity

Environmental Science & Technology, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). http://dlvr.it/4g3FRK

[environmentguru]

Novel Nitro-PAHFormation from Heterogeneous Reactionsof PAHs with NO2, NO3/N2O5, and OH Radicals: Prediction, Laboratory Studies, and Mutagenicity

Environmental Science & TechnologyDOI: 10.1021/es4043808 http://dlvr.it/4g1Qtb

[chemicals-world-blog]

Red/Yellow, FDA alerts and other properties

Yvonne Martin recently wrote about, in her experience, what works and what does not work in chemoinformatics/computational chemistry (DOI:10.1002/qsar.200610102). She based her conclusions on the 17 month usage of services provided via webpages at Abbott. In that period, almost 3 million (unique?) molecules were processed, for which the following properties were requested most, among a few others:

red/yellow alerts

FDA mutagenicity alerts

logP

Rule-of-Five

pKa

total polar surface area

solubility

Some of these can be calculated easily, and I tend towards adding those to the Molecules section of Chemical blogspace. The red/yellow and FDA mutagenicity alerts require me to define a list of substructures, and suggestions are most welcome. Martin discusses the limited accuracy of the computational calculation of LogP, pKa and other properties, but concludes that they are nevertheless used in deciding which compounds to synthesize. Organic Chemists? Now, these properties are mostly pharma oriented, and, therefore, I would like the organic chemists on our blogspace what properties you would like to see added.