Orciprenaline
Orciprenaline (INN, also known as metaproterenol) is a bronchodilator used in the treatment of asthma. Orciprenaline is a moderately selective beta2-adrenergic receptor agonist that stimulates receptors of the smooth muscle in the lungs, uterus, and vasculature supplying skeletal muscle, with minimal or no effect on alpha-adrenergic receptors. The pharmacologic effects of beta adrenergic agonist drugs, such as orciprenaline, are at least in part attributable to stimulation through beta adrenergic receptors of intracellular adenyl cyclase, the enzyme which catalyzes the conversion of ATP to cAMP. Increased cAMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from many cells, especially from mast cells.
Possible side effects
tremor
nervousness
dizziness
weakness
headache
nausea
tachycardia
Rare side effects that could be life threatening
increased difficulty breathing
rapid or increased heart rate
irregular heartbeat
chest pain or discomfort
Brand names
Alupent
Metaprel
other sources
http://www.theathlete.org/banned_drugs/alupent.html
http://www.pharphar.com/v/Orciprenaline%20Sulfate
http://www.drugsupdate.com/generic/view/365
http://dictionary.reference.com/browse/orciprenaline+sulfate
http://www.medicdirectsport.com/sportsnutrition/default.asp?step=4&pid=424
http://www.nevdgp.org.au/info/lungf/asthma-exercise-health.html
http://www.theathlete.org/banned_drugs/
http://www.drugs.com/international/orciprenaline.html