The Creation of Bubble
Caine's first npc.... holy shit... I feel like so many people forget that Bubble is the first NPC. Like he realized he was alone after consuming the blue dot and wanted companionship. Isn't that also painfully Genesis of him too.
It's not good to be alone, so God creates for himself a companion from the memory of a familiar stranger who could have been at his side had he done things differently. Rather than extract from his own side though, he imparts upon his first creation a piece of his mind (which at this point consists of dominant red and dormant blue). Like, Bubble is Caine's Adam, Eve, and Satan rolled up in one if you think about it for a little too long.
Unintentionally played into the idea that Caine created Bubble in the blue AI's image in Eve's design. Sharp teeth and wide staring eyes, spherical head. A copy of a copy. EVE was modeled after CAINE and Bubble was modeled after EVE. By being of the same nature, of the same mind, they share an innate connection well before they even have the chance to meet. The fact they never met in canon yet were also always with each other at the same time...