Tea is cultivated as a cash crop all over the world and is consumed by more than 2 billion people throughout 125 countries nowadays. It is a nutrient-dense beverage with therapeutic characteristics that has a long list of health advantages. Pathogenic attacks are becoming the main dilemma in tea plants because of the continuous and adventurous development of plant pathogens, including insect pests, fungi, bacteria, viruses. Biogenesis pathways of miRNA are vital for the development, improvement, and protection of tea plants. MiRNAs of plants play key roles in a variety of regulating networks relating to plant growth, metabolic signaling, and environmental stress reactions. Various techniques, i.e., Transcriptional gene silencing, virus-induced gene silencing, Hairpin gene silencing, co-suppression, and artificial miRNAs, all these techniques are RNA interference (RNAi) strategies that have been used to shield tea cultivars from various stressed conditions. In this review paper, we summarized recent findings of miRNA-mediated regulation, features, and the defensive system of tea cultivar’s responses to plant pathogens, particularly fungal pathogenic attacks and insect herbivory. Eventually, we concluded the novel functions of miRNA-mediated gene silencing for future research and how it can be utilized for the improvement of pathogenic attacks tolerance in transgenic tea plants.