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Lemon balm! I use this plant as an antiviral and as a sedative. It's a very mild and well tolerated example of both. It's very helpful when you have someone who can't sleep because they have a cold, for instance. Frequently i use it as a simple for acute situations and in combination with other herbs for chronic situations. . . . . #lemonbalm #herbs #herbal #phytomedicine #medicinalplants #herbalmedicine #limonene #fallcolors
Azima tetracantha L., a medicinal plant from the Salvadoraceae family, is traditionally recognized for its diverse therapeutic properties, including antimicrobial, anti-inflammatory, hepatoprotective, and hypoglycemic effects. This study aimed to screen the phytochemical constituents and evaluate the antimicrobial potential of its leaf extracts. The phytochemical analysis revealed the presence of key bioactive compounds such as tannins, flavonoids, phenolic compounds, lignin, and terpenoids in ethyl acetate and ethanol extracts. The antimicrobial activity was assessed using the disc diffusion method against various bacterial (Escherichia coli, Pseudomonas aeruginosa, Streptococcus mutans, Salmonella typhi, and Staphylococcus epidermidis) and fungal (Aspergillus niger, Aspergillus flavus, and Candida sp.) strains. The ethanol extract demonstrated the highest inhibition against Escherichia coli (11 mm), Streptococcus mutans (11 mm), and Staphylococcus epidermidis (12 mm). The ethyl acetate extract exhibited notable inhibition against Escherichia coli (8 mm) and Staphylococcus epidermidis (6 mm). The diethyl ether extract showed strong inhibition against Escherichia coli (12 mm) but was less effective against other bacterial strains. Petroleum benzene extract exhibited limited activity, with inhibition observed only against Streptococcus mutans (7 mm). Mixed solvent extracts displayed the highest inhibition against Escherichia coli (20 mm), Streptococcus mutans (20 mm), Staphylococcus epidermidis (15 mm), and Candida sp. (16–20 mm). GC-MS analysis identified several bioactive metabolites, further highlighting the pharmaceutical potential of Azima tetracantha L. The findings support its traditional medicinal use and suggest its potential role in developing novel antimicrobial agents.
The decoction of the leaves of Parquetina nigrescens (Apocynaceae) is used by Ivorian traditional healers for the treatment of inflammation. Regarding this traditional practice, the present study aimed at evaluating through outa scientific approach the anti-inflammatory activity of the aqueous extracts from Parquetinanigrescens leaves. The extracts were tested according to the model of acute rat paw oedema induced by 1% carrageenan. Several doses of phytomedicines were administered orally to the animal sand ranging as follows: 1600, 2400, 4800 mg/kg. The results obtained with the aqueous extracts of Parquetinanigrescens leaves were firstly compared with those of physiological control (NaCl 0.9%) and thereafter with those of the reference (diclofenac sodium 25 mg/kg). The comparisons were performed at 1 hour, 2 hours, 3 hours, 4 hours, 5 hours, 6 hours, 12 hours and 15 hours after injecting carrageenan into rats. The parameters considered for this purpose arethe percentage increase of paw circumference (%AUG) and the percentage inhibition of treatment (%INH). Thus, therewas a significant difference (p
Evaluation of the anti-inflammatory activity of aqueous extracts from Parquetina nigrescens (Afzel.) Bullock (Apocynaceae)
Abstract The decoction of the leaves of Parquetina nigrescens (Apocynaceae) is used by Ivorian traditional healers for the treatment of inflammation. Regarding this traditional practice, the present study aimed at evaluating through outa scientific approach the anti-inflammatory activity of the aqueous extracts from Parquetinanigrescens leaves. The extracts were tested according to the model of…
Assessing Anti-Inflammatory Properties of Parquetina nigrescens Extracts
Abstract
The decoction of the leaves of Parquetina nigrescens (Apocynaceae) is used by Ivorian traditional healers for the treatment of inflammation. Regarding this traditional practice, the present study aimed at evaluating through outa scientific approach the anti-inflammatory activity of the aqueous extracts from Parquetinanigrescens leaves. The extracts were tested according to the model of acute rat paw oedema induced by 1% carrageenan. Several doses of phytomedicines were administered orally to the animal sand ranging as follows: 1600, 2400, 4800 mg/kg. The results obtained with the aqueous extracts of Parquetinanigrescens leaves were firstly compared with those of physiological control (NaCl 0.9%) and thereafter with those of the reference (diclofenac sodium 25 mg/kg). The comparisons were performed at 1 hour, 2 hours, 3 hours, 4 hours, 5 hours, 6 hours, 12 hours and 15 hours after injecting carrageenan into rats. The parameters considered for this purpose arethe percentage increase of paw circumference (%AUG) and the percentage inhibition of treatment (%INH). Thus, therewas a significant difference (p<0.001) between the %AUG of phytomedicine treatment at different doses and those of saline (NaCl). However, for a dose of 4800 mg/kg, when administered byoralroute, the AUG of the phytomedicine are statistically the same as those of diclofenac (25 mg/kg). Comparisons of %INH leadto similar results with %AUG. This study, therefore, confirms the anti-inflammatory properties of Parquetina nigrescens leaves and emphasizes the empirical use of that plant species in the treatment of inflammation.
Introduction
Current knowledge places the beginning of humanity at around seven million years ago (Ta et al., 2023). Since that time, man has used plants (Fleurentin, 2007). This is explained by the use of plant in various areas of life (housing, health, food). The health field has given rise to a science called ethnomedicine. Ethnomedicine is defined as the set of beliefs and practices relating to illness in each given society (Laurence, 2021). It is also known as traditional medicine, which is highly developed in African countries. According to traditional medicine, no disease is incurable. It offers treatments for all kinds of diseases: cardiovascular diseases, metabolic diseases and especially inflammatory diseases. Related to inflammation, it is above all a defense mechanism, aiming to neutralize the attacking agent and eliminate damaged tissues (Souhel, 2010). In modern medicine, this health condition is treated with chemical compounds known as steroidal and non-steroidal anti-inflammatories (Ta-Bi et al., 2018). Unfortunately, these drugs provoque other health damages in humans, particularly cardiovascular diseases (Heymonet, 2013; Ta, 2017). Therefore, the use of phytomedicines is increasingly encouraged. Previous ethnomedicinal report in Côte d’Ivoire mentioned the use of Parquetina nigrescens leaves extract in the treatment of anti-inflammatory condition (N'guessan, 2008). Although no scientific investigation was performed in Côte d’Ivoire, the antiinflammatory effect of that plant species was carried out elsewhere like in Nigeria (Owoyele et al., 2009). But the methodology used in this study is different and will be of interest to compare both studies or confirm scientifically the potential of Parquetina nigrescens leaves in inflammation removing. The objective of this study is therefore to seek scientific bases of the use of leaf decoction against inflammatory diseases by traditional medicine form from Côte d’Ivoire.
Source : Assessing Anti-Inflammatory Properties of Parquetina nigrescens Extracts | InformativeBD
The decoction of the leaves of Parquetina nigrescens (Apocynaceae) is used by Ivorian traditional healers for the treatment of inflammation. Regarding this traditional practice, the present study aimed at evaluating through outa scientific approach the anti-inflammatory activity of the aqueous extracts from Parquetinanigrescens leaves. The extracts were tested according to the model of acute rat paw oedema induced by 1% carrageenan. Several doses of phytomedicines were administered orally to the animal sand ranging as follows: 1600, 2400, 4800 mg/kg. The results obtained with the aqueous extracts of Parquetinanigrescens leaves were firstly compared with those of physiological control (NaCl 0.9%) and thereafter with those of the reference (diclofenac sodium 25 mg/kg). The comparisons were performed at 1 hour, 2 hours, 3 hours, 4 hours, 5 hours, 6 hours, 12 hours and 15 hours after injecting carrageenan into rats. The parameters considered for this purpose arethe percentage increase of paw circumference (%AUG) and the percentage inhibition of treatment (%INH). Thus, therewas a significant difference (p
Phytomedicine and the necessity of funding health research in Nigeria, By Rahma Oladosu
Phytomedicine and the necessity of funding health research in Nigeria, By Rahma Oladosu
Phytomedicine is the utilisation of the therapeutic and healing properties of herbs for medicinal purposes, and this has been in existence since the advent of human civilisation. With the numerous health challenges that Nigerians face, ranging from communicable to non-communicable diseases, conventional pharmacotherapy has rather been the mainstay of treatments for a majority of conditions. Yet,…
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ANTICANCER ACTIVITY OF Pedalium murex Linn METHANOLIC LEAVES EXTRACT AGAINST A549 HUMAN LUNG CANCER CELL LINE | Asian Journal of Advances in Research
Pedalium murex (Pedaliaceae), often known as Large Caltrops, is well-known for its pharmacological applications in traditional medicine. It is said to have good therapeutic characteristics that aid in the treatment of reproductive diseases in both men and women, including impotency, nocturnal discharges, gonorrhoea, and leucorrhoea. It also comprises a treatment for urinary and gastrointestinal tract problems. Antiulcerogenic, nephroprotective, hypolipidemic, sexual enhancer, mitigating, antidermatophytic, cancer prevention agent, antibacterial, and insecticidal activities have all been investigated pharmacologically. The current review may be a compilation of information gleaned from published research papers that focuses on the phytochemical and pharmacological features of P. murex. The high concentrations of methnolic extract will be useful in producing new formulations with therapeutic and cost-effective value in the future. A549 cells were treated with Pedalium murex leaves methanolic extract for six hours, twelve hours, twenty-four hours, and thirty-six hours, and their growth was controlled after 36 hours. Please see the link :- http://mbimph.com/index.php/AJOAIR/article/view/1646
