We might know the matter of which the mad brain consists but we understand nothing of its spirit, let alone its soul. We Still have neither comprehension nor insight ´..... We are living in a time when everything dear to us - mind, experience, and culture - is being reduced to distantial data - that is, matter, behavior, and biology - as if we have become alienated from our selves. Each one to his own hobby or interest. But what is often forgotten is that if you reduce something - whether it be mind, love or madness, and whether the result is called matter, hormones or neurons - you first have to know what it is you are reducing. In other words, if madness - or love, or even God - is "located" on gene X or in brain area Y or on neuron bundle Z, what is it that is located there? What indeed is madness?
Wouter Kusters - A Philosophy of Madness - The experience of Psychotic Thinking