#scilife

[scienceisanart]

Drew my Stardew Valley farmer sona (basically just a self portrait in the sdv style)

[lenas-world-on-wheels-26]

“It takes ALL sorts to make a world” 💯🥊. #wheelchair #positivevibes #positivity #positivemindset #smile #liferollson #paragirl #scilife #sci #thedaysbeforeilostmyhair #disabilityawareness #disability #cancersurvivor #theroadisroughbutyouaretough https://www.instagram.com/p/CHwZX6JpZ12/?igshid=1bx1tyjczdu8d

[phodiduddy]

Been a hot minute since I posted any art. Got my hands on an #ipad and #iPencil and have to say I really like it. Hopefully it will get me out there drawing again. #procreate #digitalart #practicemakesprogress #quadriplegic #quaddraws #scilife #hqoproject #quadout #sketch #drawing #artistsofinstagram #art #instaart (at Arbor Trace Apartment Homes) https://www.instagram.com/p/B4Ogde7lqEf/?igshid=ak299idsg81e

[houseofmind]

2 Year Anniversary PD Update

A lot has happened since I last brought you up to speed with my life and academic endeavors. Given that my last update post was over 2 years ago, I wasn’t sure where to start. With that said, this post has been opened and worked on (and opened and worked on, and so forth) so it’s a long one :X If you’re new, welcome! Also, please be sure to check out the list of things I learned during my PhD. 

Spring/Summer 2016

Briefly, I moved to Pittsburgh about a week after that update post. I crammed as much of my stuff as I could along with Fausto (my cat) into a rental car and drove to my new place amidst a snowstorm. I made it there safely (although I had to make an overnight stop that I swear gave my cat anxiety). My new home exceeded my expectations (2 bedroom, living room, kitchen, basement, washer/dryer, short commute < $1,000), but leaving NYC and most of my friends was bittersweet. 

I went into lab the next day after arriving in Pittsburgh. THAT felt really weird because it was when reality hit. New job, new role, new boss (and new style), new techniques, new approaches, new life basically. My first challenge in the lab was learning the “bread and butter” technique: in vivo extracellular recordings of VTA dopamine neurons. Initially, this scared the shit out of me because I had 0 electrophysiology experience so I was worried about how long it would take for me to be decent and start collecting good data. I was trained by the RAP in the lab; I shadowed her for a week and copied down as much as I could. Then, I did an animal every day for a month. That’s about how long it took for me to get comfortable. (Side note: if you move to a lab and need to learn a new technique, my advice is to attack it aggressively until you learn it!). At the beginning I encountered problems such as having my animal bleed too much, giving too much anesthetic, taking too long (a whole day for just one surgery), making bad electrodes, not being able to find dopamine neurons, etc. The really cool part was seeing myself get better: not making the same mistakes, being able to correct mistakes when they happened, becoming faster and more efficient, optimizing my procedure. It was a great reminder of why I love doing science and that I am capable of learning new things :]

Then came the part where my advisor asked me to think of projects related to his prior work and funding. Call this my second challenge in the lab. He suggested a “safe” project and a “pie in the sky” project. I really appreciated his flexibility and willingness to have me choose projects and questions that I cared about, while also offering his guidance and steering me in better directions. After I pored over his grants and (then still in press papers), I came up with 2 ideas and presented my experimental design to the lab. Next, I got to work! During this time I received funding from a T32 program within the Psychiatry at Pitt, which would cover my stipend until I was able to secure my own funding (more on this in Fall 2015). 

Work was interrupted for a couple of days in May that I took off to attend my graduation in NYC. My parents and one of my brothers were able to fly in from Puerto Rico and I was really pleased. I am the only (and first!) PhD in either side of the family so I could tell that this was a big deal to them and that they were really proud of me. Obviously, this made me feel proud of myself :D

Here is a pic of me on graduation day:

After I came back, it was time to get down to business. My first cohort of “real animals” was ready for all the single unit dopamine (DA) neuron recordings I had to do. Even though I had only been doing this technique for ~2 months, I managed to get some interesting preliminary data that my PI was enthusiastic about, he suggested I write an F32 (NIH postdoctoral fellowship grant). For the August deadline, meep! Most of June and July was spent working around the clock to not only gather and analyze the data, but also write the proposal. IT WAS INSANE. During this time, I also traveled to San Sebastián in the Basque Country (within Spain) for the International Society for Developmental Psychobiology (ISDP) meeting. It was my first time out of the country since 2013 and it was quite exciting because I was awarded their dissertation prize! I was only there for 4-5 days but I managed to hang out with my PhD advisor and conference buddies, gave a talk on my dissertation research, meet some pretty cool people from all over,  take in some breathtaking views, eat pintxos, and go to the beach. I guess you could call this my “vacation” over the summer. Finally, the last exciting thing to happen over the summer was that I received an invitation from the American College of Neuropsychopharmacology (ACNP) to attend their annual meeting in December (more on this below). 

Fall/Winter 2015

After submitting my grant, I continued to perform experiments related to my F32 proposal project. I also started generating animals for another project in which I would look at the effects of chronic mild stress (i.e. depression model) in a neurodevelopmental model of schizophrenia-like deficits. I also got the grant score for my initial submission, which I knew was not within funding range so that meant resubmission in the spring. What can you do? During this semester I participated in the weekly career and research development (CARD) seminar, which is oriented towards helping postdocs gain the skills necessary for transitioning into an independent research position. This was required for me to get the T32 $$$, but I would strongly advise anyone who has access to these types of programs to attend! Topics covered included but were not limited to: how to negotiate, conflict management, how to prepare a job talk, authorship, mock K review process, etc... There is also a writing block portion of the seminar in which participants are divided into topic specific mini groups and get feedback from at least 2 other faculty on a weekly basis before grant submission. Besides being able to cultivate a positive and professional relationship with my T32 director, I’d say that the CARD seminar was the best thing about participating in this T32 program. 

In terms of travel and meetings, I attended the SfN 2015 conference in Chicago and I’ve got to say that my experience there was so positive it even made me change my mind about Chicago!!! It was the first time I was attending this meeting without having a poster so I focused on trying to meet the dopamine/electrophysiology folks and attending all the socials I could fit in :D Right after SfN, I went to NYC to visit some friends still in grad school over Thanksgiving. I cannot stress how important it is to keep in touch with your friends and make time for them. Anyhow, I got back and then it was time to fly down to Florida for the ACNP meeting. This was my first official presentation as a PD so I was really nervous (also presenting a new technique, new project, new everything!) but my boss was really supportive and the people that came by my poster were kind, insightful and encouraging. The location is also superb and the science top notch, I think this has dethroned Gordon Amygdala as my favorite meeting (most of those people were here anyway!) and I will definitely keep applying for that travel award for as long as I have to. After ACNP I flew home for Christmas and got an invitation from my advisor to co-author a review paper w/ another PD in the lab. This paper has been published already and can be found here. 

Spring 2016

I basically spent the spring working on additional experiments for my main project that I thought were necessary after presenting at ACNP and getting feedback (i.e. extra controls, increasing n, diff stats, etc...). This was a good thing because I also used some of that data for my F32 resubmission, which was due in April. As I wrote that sentence I remembered that this time was particularly busy for me in the lab as the cohort of animals for my other project (MAM-CMS) was born and I was running 2 behaviors + recording all of these animals (8 group total). It was so crazy busy (yet productive) that I swore to myself never to schedule that many experiments for the same couple of months ever again. 

Summer 2016

I presented a new and improved version of my main project poster at the Society for Biological Psychiatry in Atlanta. This was very cool because I had never been there (omg the aquarium!) and I got to reconnect with a lot of people I had met during my PhD but had not seen since the start of my PD. Apparently they really like this meeting and it is one of their go-tos. One of these people was my PhD advisor, whom I worked with on trying to wrap up and expedite my remaining PhD papers. Another person was another female minority graduate student that I knew during my PhD at NYU. It was great catching up with her and hearing about all the great science she will be doing in her PD lab and how the transition was for her. I remembered thinking that there are many paths that can lead to the same outcome, and feeling at peace. 2 interpersonal crises later, I received the score for my F32 resubmission and it was so good I A) almost fell off my chair and B) started crying (like, really). If you’re anything like me, you probably already know that you cannot have it all. It always feels like either I’m great in my personal life and so so at work or I’m killing it at work and everything else has gone to shit. To me, the score meant funding was pretty much a given, so it tipped the scales back to the killing it at work scenario and I settled for being happy with that and harnessing what was left of my happiness into that new positive direction. You can read about my F32 project here. I spent the rest of the summer celebrating my birthday, good fortune and prepping my first PD paper for submission. Also, I GOT A CAR! For the first time in nearly 7 years since I did my PhD in Manhattan and lol cars in NYC. 

Fall 2016

Remember that slump I mentioned I was in at the beginning of the summer? I decided to get over it by taking a solo trip to Thailand :] That is a post in itself (which will likely not end up here) but it was truly a once in a lifetime trip. I liked that it was hard (+16 hours to get there), new (first time ever in Asia) and was something totally out of my comfort zone. I met people from all over the US, rode elephants, visited UNESCO world heritage sites, learned about Buddhism, bar-hopped in Khao San Road and the red light district, shipped in a professional masseuse from the temples for a full body massage, ate weird food, etc. etc. Some of these pics can be found my scrolling down in my IG.  I feel like everyone should do something like that for themselves, at least every once in a while. I also learned that culture shock is funny because it can happen once you get back from your trip. I had a soft meltdown upon arriving at JFK and spent my first night back talking to a friend/processing everything I had witnessed. Can’t wait to go back and this time make it to Krabi or Phuket! 

During this semester, I also submitted my initial paper for my main project and added experiments to my secondary project. In more exciting news, I published a first author PhD paper on the effects of early life stress on social behavior and neural activity in cortical and limbic areas. You can read it here. I also got a travel award to present this work at the Society for Social Neuroscience in San Diego jus prior to SfN 2016, where I presented my first SfN poster as a PD. I was overwhelmed by the positive response and I got to do a podcast w/ Deb Budding from Neurocurious. Even though I was dead tired and delirious from my poster session being immediately before, it was SO MUCH FUN <3 I just checked and its still not up but will link it here when its available! SfN 2016 was followed by ACNP 2016 (first time presenting my MAM/CMS data, now DEFINITELY my favorite meeting), although I flew down to Florida early so I could make it to Art Basel (basically a conference, but for art!). I had such a great time that I almost forgot that my paper was rejected :( When I got back to Pitt, I focused on collecting data for the last experiments in yet another (small) project (that I have not mentioned previously yet). Then I went off to Puerto Rico to spend NYE w/ my family and friends :D

Winter 2016-2017 (aka where am I now)

I published another PhD paper. This one is a co-first paper and I’m really proud of it because it represents an effort by our group to incorporate techniques used in humans to facilitate translation of findings between animal models and humans. 

I revised and resubmitted my previously rejected paper. System says it’s still under review so we’ll see what happens... 

I submitted a grant based on an idea I had last fall that ties in nicely with my current work (pitched the idea to advisor at SfN 2016, luckily he agrees it is interesting/worth the shot).

Collected prelim data for above-mentioned grant.

Organizing the outline for a review I want to write that’s related to my grant. A colleague/mentor gave me the idea to do this since it’s a good chance to get a publication of all that lit search you did anyway! 

Put in 2 travel award applications (1 no, 1 still waiting) to present my work 

Nearly done collecting data for that random project 3 that slipped my mind for most of this post. I think this is because it’s not my main project and its a follow-up of someone else’s project. Presented this data at lab meeting and got some feedback about graphing/analyzing data. Working on this and aiming to submit by early summer. 

Traveling to Boston in 2 weeks to present in the Poverty and the Brain symposium at the Eastern Psychological Association meeting

Accepted a position as an ad hoc member of ACNP’s minority task force in order to help increase the participation of underrepresented minorities (URMs) in the college and to help retain them

Accepted a position as Review Editor in the Editorial Board of Frontiers in Behavioral Neuroscience 

WHEW. I finally got it all out. There you have it, what I’ve been up to since starting my postdoc and why I haven’t been more active on Twitter/here. Hopefully it goes someways in attenuating my I-should-be-posting-more-guilt :P 

Also, please feel free to write if you have any questions about PD life, the grad to PD transition or anything else you have read about here : ) In case you didn’t know, I started this blog as a grad student who DID NOT think they were going to make it in academia so the fact that this blog is still alive and so many of you still follow it/engage motivates me to keep it going for as long as I can. Maybe one day I’ll have a job and can look back at everything that led to that there. That’s the dream. Until next time! 

xoxo

Dr. M

[scienceisanart]

Made an updated PNG model for my streams, I really vibe with this one <3

[scienceisanart]

Redraw of an old piece from 2014

[scienceisanart]

last week my friend asked me if i wanted to get coffee with him and when i asked if it was intended to be a date he stammered and eventually said nah, but he just asked me out for realsies and chat look what i found on his bluesky

god he's so precious QwQ

[scienceisanart]

Fuck it, custom pride icons like this for 50 USD so I can have spending money at this year's pride fest :3

Dm for details!