Since Transformers're living beings, they obviously get sick, and diseases definitely exist. That's why there're medics. However, how do they get vaccinated, and do they even need to?
Dear Contagion Concerned,
In the same way that your own immune systems seek out and eliminate pathogens before they can infect your body, so too are our own internal workings protected by intricate, interconnected mechanisms that you might call an “immune system”. Our brain modules are heavily encrypted and secured behind what you would call a “firewall”, while our physical bodies are protected by a complicated system of ultra-thin, electrostatically charged plates that attract and filter out environmental hazards like sand, dust, and rust flakes.
However, these systems are not perfect, and in an ever-changing world Cybertronians must constantly update their software—and, in extreme cases, the hardware itself. When Cybertronians arrive on new worlds, their internal systems analyze the atmospheric conditions and geology of the local terrain and adapt their system accordingly. However, these kinds of ad-hoc reconfigurations are not enough to withstand the very worst diseases known to our species, and in these cases more drastic measures must be taken. In times of postwar prosperity, these campaigns take the form of “Quantum Cycle Upgrades”, where both Maximals and Predacons receive mandatory hardware and software packages that would bring them up to a consistent standard. By the time of the Spark War, the Maximal Imperium and the Predacon Alliance had, over the course of multiple upgrade cycles, worked together to stamp out 73% of all Transformer diseases, including Cosmic Rust, cybercrosis, and Corrodia Gravis.
However, in times of war, where the Cybertronian race is scattered across the galaxy and the worst of our kind concoct monstrous bioweapons, this kind of "herd immunity" is impossible, as is any kind of organized, species-wide response to a disease outbreak. Depending on the resources at hand, individual Cybertronians might have to adopt entirely new bodies in order to fight off an infection-as was the case when the Earth Defense Command transferred the minds of many Autobots and Decepticons into custom-built Binaltech bodies in order to stave off a debilitating Cosmic Rust infection, or when the Oracle reformatted Optimus Primal's Maximals into technorganic frames immune to Megatron’s transformation virus.













