Nearly a year in space changed Scott Kelly’s genes, brain function and more, NASA’s Twin Study shows.
For nearly a year, identical twins Scott and Mark Kelly lived in different worlds — literally. Mark enjoyed Earth-bound retirement in Tucson, Ariz. Meanwhile, Scott floated in microgravity aboard the International Space Station some 400 kilometers (250 miles) above the planet. That year apart has given scientists the clearest look yet at how long-term spaceflight can affect the human body.
Ten science teams in NASA’s Twins Study examined the brother astronauts before, during and after Scott’s 340 days in space. The teams studied each twin’s body functions. They ran memory tests. And they examined the men’s genes, looking what differences might be due to space travel.
The long-awaited results appeared April 12 in Science. They confirm that lengthy space travel stresses the human body in many ways. Space living can change genes and send the immune system into overdrive. It can dull mental reasoning and memory.
Scientists Say: Orbit
This is “the most comprehensive view that we’ve ever had of the response of the human body to spaceflight,” says Susan Bailey. She studies radiation and cancer at Colorado State University in Fort Collins. She also led one of the NASA research teams. She says it’s still unclear, however, whether the changes seen will cause long-term harm.
NASA has big plans for the future of human spaceflight. The space agency’s proposals to send long-term, crewed missions to the moon and, eventually, land astronauts on Mars will require significant advances in rocket and spaceflight hardware. But along with new technology, scientists are grappling with another crucial question: Can the human body sustain itself during that much time in space? An exploratory Mars mission could take two or three years, while most space expeditions so far have lasted six months or less. Extended missions beyond Earth orbit could result in profound, and potentially dangerous, biological effects in astronauts’ bodies.
To study the influence of microgravity, radiation and confinement in long-duration spaceflight, NASA selected twins Scott and Mark Kelly for a unique mission. The two identical twins have both served as NASA test pilots and astronauts, and Scott was chosen for a yearlong mission to the International Space Station (ISS), leaving his brother—a genetic copy of himself—down on Earth. Researchers used the earthbound Mark as a kind of control subject to compare to any changes in Scott during his year in space, which lasted from March 27, 2015 to March 1, 2016.