#urosurgeon

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👉 Early signs of prostate disease may include frequent urination (especially at night), a weak or interrupted urine flow, difficulty starting or stopping urination, pain or burning during urination, and sometimes blood in urine or semen. These symptoms should not be ignored, as they could indicate an underlying prostate condition such as an enlarged prostate, prostatitis, or even prostate cancer. If you notice any of these issues, it’s important to consult a urologist promptly for proper evaluation and timely treatment. Consult our urologist and prostrate cancer specialist in Vidyasagar CHS Navi Mumbai—early detection saves lives.

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Amazing Secrets of Kidney Stone Care in Gujarat. A Comprehensive Guide for Gujarat Residents

                                                                                Introduction: Kidney stones are a common urological condition affecting millions worldwide, and Gujarat is no exception. The state’s hot climate, dietary habits, and genetic predispositions contribute to a higher incidence of kidney stones among its population. This blog aims to provide a comprehensive understanding…

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Prostate Cancer- Stages: PART 2

Determining the stage of Prostate Cancer

The stage, or how far the cancer has spread, is an important part of assessing prostate cancer. When choosing therapies, knowing the stage helps define the prognosis. The four-stage TNM system, abbreviated as Tumor/Nodes/Metastases, is the most prevalent one. It is made up of the size of the tumor, the number of lymph nodes that are involved, and whether or not there are any other metastases.

Whether or not the cancer is still confined to the prostate is the most crucial distinction made by any staging system. Clinical T1 and T2 cancers are only found in the prostate in the TNM system, whereas T3 and T4 cancers have spread elsewhere. There are a number of tests that can be used to find signs of spread. When a doctor diagnoses early prostate cancer with a low risk of metastasis, medical specialty professional organizations advise against using PET, CT, or bone scans. When a CT scan looks for spread in the pelvis, a bone scan looks for spread to the bones, and endorectal coil magnetic resonance imaging looks closely at the prostatic capsule and seminal vesicles, those tests would be appropriate.

A pathologist examines the samples under a microscope following a prostate biopsy. The grade of the tumor is reported by the pathologist if cancer is present. The grade indicates the likelihood of the tumor growing quickly and how significantly the tumor differs from normal prostate tissue. Prostate tumors are graded using the Gleason system, which assigns a score between 2 and 10, with a score of 10 representing the most abnormalities. The pathologist gives the pattern that is seen most frequently under the microscope a number between one and five, and they do the same for the pattern that is seen second most frequently. The Gleason score is the sum of these two numbers. Another approach that is sometimes utilized is the Whitmore-Jewett stage.

Dr. Amit Ghosh is one of the best urologist and robotics uro-surgeon in Kolkata. After his return from the UK, he has been associated with various institutions including Wockhardt Hospital and Kidney Institute, Woodlands Hospital, Kothari Medical Center and Anandalok Hospital. Currently he is dedicated to his service to Apollo Gleneagles Hospitals, Kolkata. Currently he has developed a very well established and robust Urological presence in the campus of Apollo Gleneagles Hospitals, Kolkata. The practice takes care of all fundamental general Urological procedures, a vast multi-disciplinary Uro Oncology specialty, and also a comprehensive diagnostic and uro health check-up facility.

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Olaparib (Lynparza)

Olaparib is a PARP inhibitor, which is a type of targeted therapy. It is supported for patients with metastatic maiming safe prostate disease whose sickness has proceeded to develop and spread during therapy with abiraterone or potentially enzalutamide and who have DNA-fix quality deformities, which might be acquired or in the growth. Cancer cells have a harder time repairing damaged DNA because of defects in DNA repair genes. DNA-repair gene defects are associated with certain genes, including BRCA1, BRCA2, and a number of others; the presence of any of these genes makes olaparib treatment possible. The FDA has likewise endorsed 2 explicit tests to choose patients for treatment with olaparib.

Dr. Amit Ghosh is one of the best urologist and robotics uro-surgeon in Kolkata. After his return from the UK, he has been associated with various institutions including Wockhardt Hospital and Kidney Institute, Woodlands Hospital, Kothari Medical Center and Anandalok Hospital. Currently he is dedicated to his service to Apollo Gleneagles Hospitals, Kolkata. Currently he has developed a very well established and robust Urological presence in the campus of Apollo Gleneagles Hospitals, Kolkata. The practice takes care of all fundamental general Urological procedures, a vast multi-disciplinary Uro Oncology specialty, and also a comprehensive diagnostic and uro health check-up facility.

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Systemic treatments

Medication to eradicate cancer cells may be part of the treatment plan. To reach cancer cells throughout the body, medication may be administered through the bloodstream. Systemic therapy refers to the administration of medication in this manner.

Androgen-deprivation therapy (hormonal therapy): Since prostate disease development is driven by male sex chemicals called androgens, bringing down levels of these chemicals can assist with easing back the development of the malignant growth. Testosterone is the most prevalent androgen. In order to lower testosterone levels in the body, androgen-deprivation therapy (ADT), also known as hormonal therapy, is used either surgically (surgical castration) or medically (medical castration) to remove the testicles. The primary objective of lowering testosterone levels is more important than the choice of hormonal therapy.

Dr. Amit Ghosh is one of the best urologist and robotics uro-surgeon in Kolkata. After his return from the UK, he has been associated with various institutions including Wockhardt Hospital and Kidney Institute, Woodlands Hospital, Kothari Medical Center and Anandalok Hospital. Currently he is dedicated to his service to Apollo Gleneagles Hospitals, Kolkata. Currently he has developed a very well established and robust Urological presence in the campus of Apollo Gleneagles Hospitals, Kolkata. The practice takes care of all fundamental general Urological procedures, a vast multi-disciplinary Uro Oncology specialty, and also a comprehensive diagnostic and uro health check-up facility.

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Focal therapies

Focal therapies are treatments that target small prostate tumors without affecting the rest of the prostate gland and require less surgery. These treatments use heat, cold, and other techniques to treat cancer, mostly prostate cancer with a low or intermediate risk.

Cryosurgery: Cryosurgery, also known as cryotherapy or cryoablation, involves freezing cancer cells with a metal probe inserted through a small incision in the skin sac containing the testicles between the rectum and scrotum.

High-intensity focused ultrasound (HIFU): Focused therapy using heat is called HIFU. An ultrasound probe is inserted into the rectum during HIFU treatment, and sound waves are directed toward cancerous areas of the prostate gland. The goal of this treatment is to limit damage to the prostate gland as a whole while simultaneously eliminating cancer cells.

Dr. Amit Ghosh is one of the best urologist and robotics uro-surgeon in Kolkata. After his return from the UK, he has been associated with various institutions including Wockhardt Hospital and Kidney Institute, Woodlands Hospital, Kothari Medical Center and Anandalok Hospital. Currently he is dedicated to his service to Apollo Gleneagles Hospitals, Kolkata. Currently he has developed a very well established and robust Urological presence in the campus of Apollo Gleneagles Hospitals, Kolkata. The practice takes care of all fundamental general Urological procedures, a vast multi-disciplinary Uro Oncology specialty, and also a comprehensive diagnostic and uro health check-up facility.

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Targeted therapy for prostate cancer

Targeted therapy is a treatment that targets the cancer’s specific genes, proteins, or the tissue environment that contributes to cancer growth and survival. This type of treatment blocks the growth and spread of cancer cells and limits damage to healthy cells.

Targeted therapy for prostate cancer includes:

Olaparib (Lynparza): Olaparib is a PARP inhibitor, which is a type of targeted therapy. It is supported for patients with metastatic maiming safe prostate disease whose sickness has proceeded to develop and spread during therapy with abiraterone or potentially enzalutamide and who have DNA-fix quality deformities, which might be acquired or in the growth. Cancer cells have a harder time repairing damaged DNA because of defects in DNA repair genes. DNA-repair gene defects are associated with certain genes, including BRCA1, BRCA2, and a number of others; the presence of any of these genes makes olaparib treatment possible. The FDA has likewise endorsed 2 explicit tests to choose patients for treatment with olaparib.

Rucaparib (Rubraca): Rucaparib is another approved PARP inhibitor for the treatment of metastatic castration-resistant prostate cancer in patients with an inherited or tumor-associated BRCA1 or BRCA2 mutation whose disease has not been controlled by abiraterone, enzalutamide, or chemotherapy.

One or more tests must be given to determine whether a patient may receive olaparib or rucaparib:

Testing for an inherited, or germline, mutation after discussion with a genetic counselor

Genomic sequencing of tumor tissue

Genomic sequencing of the tumor DNA floating in the bloodstream

Tissue from a new biopsy or tissue from a previous collection can both be subjected to genomic sequencing. Germline transformation testing alone distinguishes about a portion of the patients qualified for this treatment. All three of the aforementioned tests should be discussed with patients with metastatic prostate cancer who are considering targeted therapy.

Dr. Amit Ghosh is one of the best urologist and robotics uro-surgeon in Kolkata. After his return from the UK, he has been associated with various institutions including Wockhardt Hospital and Kidney Institute, Woodlands Hospital, Kothari Medical Center and Anandalok Hospital. Currently he is dedicated to his service to Apollo Gleneagles Hospitals, Kolkata. Currently he has developed a very well established and robust Urological presence in the campus of Apollo Gleneagles Hospitals, Kolkata. The practice takes care of all fundamental general Urological procedures, a vast multi-disciplinary Uro Oncology specialty, and also a comprehensive diagnostic and uro health check-up facility.

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KIDNEY STONE

Kidney Stone- Part 2

Treatment

Treatment for kidney stones varies, depending on the type of stone and the cause.

Small stones with minimal symptoms

Most small kidney stones won't require invasive treatment. You may be able to pass a small stone by:

Drinking water: Your urine will be less concentrated and less likely to contain stones if you drink as much as 2 to 3 quarts (1.8 to 3.6 liters) per day. Drink enough fluid, ideally mostly water, to produce clear or nearly clear urine unless your doctor tells you otherwise.

Pain Relievers: A small stone can be uncomfortable to pass. For mild pain relief, your doctor may recommend pain relievers such as ibuprofen (Advil, Motrin IB, others) or naproxen sodium (Aleve).

Medical therapy: To help you get rid of your kidney stone, your doctor may prescribe medication. An alpha blocker is a medication that helps you pass a kidney stone more quickly and with less pain by relaxing the muscles in your ureter. Examples of alpha blockers include tamsulosin (Flomax) and the drug combination dutasteride and tamsulosin (Jalyn).

Large stones and those that cause symptoms

More extensive treatment may be required for kidney stones that are too large to pass on their own, cause bleeding, damage to the kidney, or persistent infections of the urinary tract.

Dr. Amit Ghosh is one of the best urologist and robotics uro-surgeon in Kolkata. After his return from the UK, he has been associated with various institutions including Wockhardt Hospital and Kidney Institute, Woodlands Hospital, Kothari Medical Center and Anandalok Hospital. Currently he is dedicated to his service to Apollo Gleneagles Hospitals, Kolkata. Currently he has developed a very well established and robust Urological presence in the campus of Apollo Gleneagles Hospitals, Kolkata. The practice takes care of all fundamental general Urological procedures, a vast multi-disciplinary Uro Oncology specialty, and also a comprehensive diagnostic and uro health check-up facility.