1.12
SAM: But if you know evil's out there, how can you not believe good's out there, too?
DEAN: Because I've seen what evil does to good people.
2.13
DEAN: There was nothing protecting her. There's no higher power, there's no God. I mean, there's just chaos, and violence, and random unpredictable evil th - that comes out of nowhere, and rips you to shreds.
4.02
DEAN: See, this is why I can't get behind God.
SAM: What are you talking about?
DEAN: If he doesn't exist, fine. Bad crap happens to good people. That's how it is. There's no rhyme or reason - just random, horrible, evil - I get it, okay. I can roll with that. But if he is out there, what's wrong with him? Where the hell is he while all these decent people are getting torn to shreds? How does he live with himself? You know, why doesn't he help?
4.02
DEAN: I'm not convinced. 'Cause if there's a God, what the hell is he waiting for, huh? Genocide? Monsters roaming the earth? The freaking apocalypse? At what point does he lift a damn finger and help the poor bastards that are stuck down here?
CASTIEL: The Lord works…
DEAN: If you say "mysterious ways," so help me, I will kick your ass.
5.02
DEAN: Listen, Chuckles, even if there is a God, he is either dead—and that's the generous theory—
CASTIEL: He is out there, Dean.
DEAN: —or he's up and kicking and doesn't give a rat's ass about any of us. I mean, look around you, man. The world is in the toilet. We are literally at the end of days here, and he's off somewhere drinking booze out of a coconut. All right?
5.16
DEAN: So he’s just going to sit back and watch the world burn?
JOSHUA: I know how important this was to you, Dean. I’m sorry.
DEAN: Forget it. Just another dead-beat dad with a bunch of excuses, right. I’m used to that. I’ll muddle through.
5.22
CASTIEL: I don't know what God wants. I don't know if he'll even return. It just… seems like the right thing to do.
DEAN: Well, if you do see him, you tell him I'm coming for him next.
8.14
KEVIN: I-I guess. Uh, he works in mysterious ways.
DEAN: Yeah, mysterious, douche-y ways.
10.16
DEAN: I believe there is a God. But I’m not sure he still believes in us.
11.03
SAM: Well, God kicked this thing's ass once before, right?
DEAN: Yeah, it'd be nice if he put down the Mai Tai and show up for work.
11.04
DEAN: And you think that this thing is God? Come on. How many -- how many opportunities has God had to crack this pinata, and I don't see any candy on the floor, do you?
SAM: Okay, then maybe it's not God. But uh . . .
DEAN: I know what you're trying to do here. You're trying to find some -- some greater meaning to it all. Right? Some . . . Fate to what went down. But I'm telling you, Sam. The Darkness? It's on us. And no one's gonna help us, certainly not God.
11.21
DEAN: Here's the thing, um...Chuck... And I mean no disrespect. Um... I'm guessing you came back to help with the Darkness, and that's great. That's, you know – It's fantastic. Um, but you've been gone a – a... long, long time. And there's so much crap that has gone down on the Earth for thousands of years. I mean, plagues and wars, slaughters. And you were, I don't know, writing books, going to fan conventions. Were you even aware, o-or did you just tune it out?
CHUCK: I was aware, Dean.
DEAN: But you did nothing. And, again, I-I'm not trying to piss you off. You know, I don't want to turn into a pillar of salt.
CHUCK: I actually… didn't do that.
DEAN: Okay. People – People pray to you. People build churches for you. They fight wars in your name, and you did nothing.
11.21
DEAN: The deal? What... She's gonna eliminate you, and then she's gonna destroy everything that you've created. She's told me this personally. You started this. You started all of this, but does that give you the right to end it? You know, we're not just some toys you throw away. I think you owe us more than that.
CHUCK: If my plan doesn't work, then humans will step up. You, Sam, others that are the chosen will have to find a way. It's why I saved you years ago. You're the firewall between light and darkness.
DEAN: No. No, I... Look, give me a – a vampire, and I'm good. But this – God's sister? That is way above my pay grade.
13.01
flashback!DEAN: Okay, Chuck… or god, or whatever. I need your help. See, you– you left us. You left us. You went off. You said… You said the earth would be fine because it had me… and it had Sam, but it’s not, and we’re not. We’ve lost everything. And now you’re gonna bring him back. Okay? You’re gonna bring back Cas, you’re gonna bring back Mom, you’re gonna bring ‘em all back. All of ‘em. Even Crowley. ’Cause after everything that you’ve done, you owe us, you son of a bitch. So you get your ass down here and you make this right, right here and right now. Please. Please help us.
present!DEAN: God's not listening. He doesn't give a damn.
13.02
SAM: Yeah. Um, God basically… created everything.
DEAN: Yeah, and then he skipped out, leaving guys like us to clean up his messes like Lucifer.
13.15
DEAN: God? He doesn’t give a damn about you or me or anyone else. So, if you’re expecting some sort of a-a miracle to happen, well… good luck.
14.19
SAM: But we know the truth. We know God is real. We know angels are real, too.
DEAN: God writes paperback books in his underwear, okay? And angels are dicks.
15.07
DEAN: Besides, who's gonna look out after the little guy? God certainly isn't.
DEAN: Screw you, Chuck. (15.17)