The BiologicsCorp bioprocess facility provides microbial fermentation services using 5L to 1000L fermentors. Large-Scale & High-Density.
The BIC (BiologicsCorp) bioprocess facility provides services in microbial fermentation. It features a 1,000 sq. ft. pilot scale fermentation laboratory capable of handling class II organisms, an adjoining 500 sq. ft. bench scale cell culture, and fermentation laboratory with multiple fermentors and bioreactors for microbial. The facility can manufacture recombinant proteins and metabolites, as well as media optimization and cell culture scalability experiments. The fermentation facility provides you with seed culture development and culture scale-up from shake flasks to pilot scale fermentors.
Two benchtop fermentors configured with five-liter vessels are available for comparative studies. Batch, fed-batch and continuous cultures of 5 to 500 liters of yeast, bacteria are produced under stringently controlled conditions using four state-of-the-art fermentors.
At the pilot scale, two 100-liter fermentors and one 500-liter fermentor are available. Constant monitoring of each run ensures the pH, temperatures, aeration, dissolved oxygen content and agitation rate can be stringently controlled. As a result we are able to accurately reproduce growth conditions to provide consistency in the quality of product produced. Support equipments include shaker incubators, laminar flow hoods, chemical hoods, clean steam, microscopes, autoclaves, cryostorage, and freeze-dryers.
It is accessible to add nutrients or induction chemicals at any point during a run. Addition of nutrient and components during the run allows fed-batch and induction experiments to be performed. Optimization experiments can also be achieved, as regular sampling through a sterile sample port is possible during the fermentation.
Quality control is maintained by regular vessel sampling, and metabolite testing ensures the final product meets your specification. The product can be sent as a frozen cell pellet or further processed to produce concentrated protein extracts.
