"During the past twenty-five years, I have worked toward developing a complex body of art that has at various times employed photographs, text, fabric, audio, digital images, installation, and, most recently, video. My work has led me to investigate family relationships, gender roles, the histories of racism, sexism, class, and various political systems. Despite the variety of my explorations, throughout it all it has been my contention that my responsibility as an artist is to work, to sing for my supper, to make art, beautiful and powerful, that adds and reveals; to beautify the mess of a messy world, to heal the sick and feed the helpless; to shout bravely from the roof-tops and storm barricaded doors and voice the specifics of our historic moment."
She moved out of her parents' home at the age of 16, and she soon moved to San Francisco to study modern dance with Anna Haplin. She decided to continue her arts schooling and attended the California Institute of the Arts, Valencia. She graduated at the age of twenty-eight with her BA. She received her MFA from the University of California, San Diego. Weems also participated in the graduate program in folklore at the University of California, Berkeley.