Central Biohub

              Central BioHub facilitates the acquisition of human biospecimens by connecting global biomedical researchers and scientists to biospecimen suppliers across the globe.         

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FFPE samples-Types, Uses and Preparation

Formalin-fixed paraffin-embedded tissue specimens, often called FFPE samples, are a fantastic material for understanding human biology and disease pathways. It is widely used in clinical diagnosis and biological and medical research, especially in cancer and rare disease research. Due to the worldwide acceptance of in-vitro research, FFPE sample studies are critical for assessing morphology, molecular characteristics, and protein structure in human tissues. Furthermore, in contemporary medical research, using FFPE tissues for molecular pathological detection, such as tumor-related gene mutations and molecular detection of targeted drugs, has progressed rapidly from scientific research to in-vitro pathological diagnosis. Furthermore, retrospective gene research is becoming more popular in tumor molecular biology. However, because most tissue samples used in scientific research are FFPE tissue blocks and FFPE tissue sections, the amount of DNA and RNA extracted from them directly impacts the outcome of molecular experiments.

How are FFPE samples prepared?

FFPE is a subset of the human biospecimen preservation method that has been in use for many years. Collecting tissue specimens from disease-state or healthy human donors is the first step in preparing FFPE samples. The extraction of specimens is mainly done during biopsies and clinical and surgical procedures by a trained medical doctor or surgeon. The excised human samples are immersed in 10% neutral buffered formalin for at least 24 hours. This process is known as formalin fixation. Later, the fixed samples are dehydrated with ethanol concentrates. The tissue is then embedded in paraffin wax to create FFPE blocks, which preserve the proteins and tissue structures. Finally, these FFPE blocks are sectioned into specific sizes to prepare FFPE specimens that are investigated and authorized by a certified histopathologist for research use. FFPE samples in the form of FFPE blocks, curls, and slides can be stored for long years without degradation. Moreover, FFPE is stored at room temperature and thus does not require highly sophisticated and expensive tissue preservation units.

Discover 6000+ richly characterized FFPE samples for research.

The quality of the research specimens directly impacts the quality of the research outcome. In modern human tissue research, well-preserved, well-annotated human tissue samples can transcribe the patient disease journey for the researchers to lead them on the right track for active translational and precision medicine research. 

Accelerating human tissue research across the globe, Central BioHub introduces the world’s most extensive inventory of reliable, high-quality FFPE samples ideal for drug and diagnostic research and development. If you are searching for top-quality human tissue for research, navigating through the inventory of Central BioHub is exciting. Explore their portfolio and order FFPE blocks and tissue samples online: https://centralbiohub.de/blogs/order-well-characterized-ffpe-samples-for-cancer-research.

Central BioHub provides a wide range of pathologist-reviewed, well-annotated FFPE blocks subjected to rigorous quality control practices procurable online at competitive prices. The tissue samples are collected and processed according to IRB protocols, safety standards, and biobanking guidelines. To learn more about FFPE samples and the service offered by Central BioHub, browse the inventory and book your research samples today.

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Sepsis is a blood poisoning condition resulting from an infection elsewhere in the body requiring immediate treatment to prevent sepsis shock.

To support in-vitro research on sepsis, Central BioHub offers you the world's largest human biospecimen inventory, which includes thousands of human serum and plasma samples from patients who have been diagnosed with sepsis or who are suspected of having it. We offer  Peripheral blood from sepsis patients of various ages, genders, and races i.e Sepsis disease samples are meticulously tested for sepsis biomarkers such C-reactive protein (CRP), procalcitonin (PCT), bilirubin, creatinine, D-dimer, and lactate dehydrogenase. For a successful study, samples are additionally hyper-annotated with a complete clinical data profile, medical histories, and patient demographics. Use advanced search options by clicking CLINICAL DIAGNOSIS, ICD-10-CM CODES, and LABORATORY PARAMETERS.

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Order human serum samples for research and development purposes online . We offer human serum critically isolated from human whole blood samples.

The serological test is primarily used to identify and measure the blood biomarkers and pathogenic antibodies. Doctors and researchers widely utilize human serum testing to diagnose diseases, monitor medication response, and measure the severity of disorders. Presenting the largest  collection of human serum samples to research, Central BioHub makes the process of procuring human  biospecimens simpler than ever. We offer human serum samples collected from  patients and healthy donors explicitly tested for  common blood biomarkers, disease-specific biomarkers, disease antibodies, autoantibodies, and more. Explore our inventory  and secure your research samples today.

https://centralbiohub.de/blogs/largest-collection-of-human-serum-samples-for-research

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Order acute hepatitis samples online. Hepatitis is a liver disease caused by HAV, HBV, HCV that affect the liver causing chronic and acute hepatitis.

Hepatitis is a fatal liver infection brought on by many hepatotropic viral strains; specifically, Hepatitis is a fatal liver infection brought on by many hepatotropic viral strains, specifically the hepatitis A virus (HAV), hepatitis B virus (HBV), and hepatitis C virus (HCV). The persistent inflammation of liver cells causes harm to liver functioning, scarring of liver tissues, and cirrhosis. Central BioHub brings thousands of serum and plasma samples to researchers through the most reputable online marketplace for human biospecimens. Managing biospecimens at Central BioHub is tailored to biorepository best practices and complies with all ethical and CDC standards.

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Procuring human biospecimens is easier than ever before. Central BioHub offers a vast Inventory with millions of human biosamples handled with utmost care.

Order human biospecimens online from Central BioHub 

Obtaining human biospecimens for your upcoming research project is faster now. Central BioHub is a leading online human biomaterial marketplace dedicated to easing the acquisition of high-quality human biospecimens for research and development.  Since its inception in 2017, Central BioHub has served hundreds of prominent pharmaceuticals, diagnostic, biotechnology, educational, government, and quasi-research organizations to fulfil their research needs. As a result, we are happy to be known as the leading provider of human biospecimens with a large customer base. Explore our inventory now to find matching human biospecimens matching your research interest.

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Procure Respiratory tract infection biospecimens Online. Procure flu, COVID-19, tuberculosis, RSV, pneumonia and more research samples from central BioHub.

The present era is witnessing a considerable rise in the incidence and prevalence of respiratory tract infections. Commonly reported infections are URTI and LRTIs, such as bacterial and viral pneumonia, Covid-19, Influenza (Flu), Tuberculosis, and RSV infection. It is often difficult to tackle the infection and improve the recovery of the patients. Therefore, intensive research is necessary to develop novel drugs and diagnostics to fight against respiratory infections. Central BioHub presents a full range of human biospecimens such as serum, plasma, and Nasopharyngeal swabs in different media isolated and tested for respiratory pathogens and specific disease parameters. The samples are intended for research and are available for online procurement. Explore the inventory and secure your research samples online.

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Explore the largest inventory of precious human biospecimens collected from consented healthy and disease-state donors exclusively for drug and diagnostic R & D.  Get immediate access to 800,000+ valuable human biospecimens  in well-preserved condition with related clinical data profile. We offer human serum, plasma, whole blood, CSF, urine, saliva, DNA/RNA  intended for research use.  All samples are hyper-annotated with tested laboratory values, detailed diagnosis and clinical data profile, and donor demographic information like age, gender, ethnicity, BMI, etc.

https://centralbiohub.de/blogs/millions-of-healthy-donor-and-disease-state-samples-online

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Order healthy donors blood samples for clinical research. Get wide range of high-quality serum, plasma, whole blood samples online.

The term "healthy donor samples" refers to varied human biomaterials such as serum, plasma, feces, urine, saliva, and whole blood samples obtained from donors whose self-reporting indicates that they are in good health. The samples are voluntarily donated by individuals of all ages, genders, and nationalities. The Central Biohub offers a vast inventory of self-reported healthy donor samples that serve as the ideal control for testing or calibrating diagnostic procedures and devices in medical research. Also, healthy donor samples can make a substantial contribution to population studies and in-vitro human epidemiological research.

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Allergy or an allergic reaction is a natural respose to allergens to expel it. Order common allergy diseases samples online for research and development.

Allergy is an acute allergic reaction that usually starts in few minutes after getting sensitized by allergens. Sneezing, itchy, red, and watery eyes, shortness of breath, coughing, dermatitis, skin rashes, and swollen lips, face, and tongue are a few of the typical allergy symptoms. The severity of allergy symptoms, however, varies greatly from person to person. Patients with severe allergic disorders have more severe allergy symptoms leading to anaphylaxis. It is potentially life threatening severe allergic reaction charactreised by severe respiratory distress, multiple organ failure, confusion, dizziness, and fainting.

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Order Alzheimer's disease patient samples.Alzheimer's disease symptoms includes dementia,cognitive functions loss in various stages of Alzheimer's disease.

Alzheimer's disease is a neurological condition that affects brain leading to memory loss. It is the most typical reason for dementia in people. Due to cognitive impairment and the loss of social and behavioral skills, patients with Alzheimer's disease are unable to function independently.Risk factors for Alzheimer's disease are family history and increased age. However, the exact etiology of the illness is still unclear. Accelerating Alzheimer's disease research globally, Central BioHub offer meticulous collection of human biospecimens exclusively for research.Hurry up, order directly from website.

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Order urine samples for biomedical research. Urine analysis is the method of general urine examination to diagnose diseases and overall health status.

Urine samples are analyzed to determine general health issues. A variety of laboratory techniques are used in urine analysis to examine how the body physiologically works. It is one of the most accurate diagnostic methods available, and it is also simple and affordable to use. By examining the chemical and physical properties of urine, it enables accurate identification of diseases like urinary tract infections, renal illnesses, endocrine abnormalities, liver diseases, and vascular disorders.

https://centralbiohub.de/blogs/wide-range-of-human-urine-samples-online

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Order liver disease samples of patients suffering from hepatitis, cirrhosis, fatty liver, nonalcoholic fatty liver disease for research and development.

Liver diseases are acute and chronic inflammation of the liver caused by viruses, hereditary factors, alcohol consumption, autoimmune disorders, cancer, medicines,etc. Often liver disease remains undiagnosed due to its asymptomatic nature in the early stage. Biospecimen procurement has never been easier, thanks to Central BioHub, an innovative digital marketplace that connects global biospecimen suppliers with researchers. The Central BioHub delivers thousands of high-quality, well-annotated human biospecimens to the research community, including serum and plasma samples from people with non-alcoholic steatohepatitis and other liver diseases.Explore our inventory to place orders.

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Order metabolic disorders samples for research. Major risk factors for metabolic syndrome are high blood pressure, abdominal fat, and type 2 diabetes mellitus

The production of energy from our diet is required for normal metabolism to maintain body function. Metabolic diseases are a group of ailments that can cause disturbance in the body's normal metabolism. It is a complex problem that raises the risk of chronic illnesses such as cardiovascular disease, diabetes, and other endocrine disorders in people of all ages and genders. The incidence and prevalence of metabolic illnesses have risen considerably in recent decades as per reports by WHO and the CDC.

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Order autoimmune thyroid disease samples online. We offer biospecimens of hypothyroidism, hyperthyroidism, Hashimoto's thyroiditis and Graves disease.

A multitude of human biospecimens are made accessible for researchers via the Central BioHub to promote  autoimmune thyroid disease research worldwide.  We offer human serum and plasma samples of the highest quality obtained from people who have Graves' disease and Hashimoto's thyroiditis. The samples are rigorously examined for anti-thyroid peroxidase and thyrotropin receptor antibodies  anti-MAK and readily available for purchase through our online human biospecimen marketplace. Hurry up,begin your journey with Central BioHub.

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Order type 1 diabetes mellitus patient samples for clinical research.Juvenile diabetes starts at early ages and is similar to type 2 diabetes symptoms.

Type 1 diabetes, also referred to as insulin-dependent diabetes mellitus (IDDM), is a kind of diabetes that interferes with how the body uses sugar spurred on by the production of autoantibodies, such as insulin and islet cell antibodies, by macrophages and T lymphocytes against beta-cell antigens. Children and young adults are typically where it begins. Consequently, it is also known as juvenile diabetes. Additionally, type 1 diabetes has become increasingly common over the past ten years, which has a negative impact on the quality of life for the younger population.

https://centralbiohub.de/biospecimens/metabolic-disorders/diabetes-i

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Order parkinson's disease samples for research.Parkinsonism a movement disorder,with no cure.Timely treatment can help improve parkinson's disease symptoms.

Parkinson's disease is a neurodegenerative condition characterized by motor deficits brought on by Lewy bodies and dopaminergic neuron loss in the substantia nigra. It mainly affects the upper and lower extremities, including  facial muscles of the patient.  Since Parkinson's disease has become more prevalent in recent years, more research is needed to create cutting-edge diagnostic procedures and treatment options to manage the condition. Central BioHub is a leading online human biospecimen marketplace offering thousands parakinson's disease biological samples immediately available for online procurement.Hurry up, order online.

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Procure FFPE Samples and FFPE block collected from cancer patients ideal for human tissue research. The samples are well defined with clinical profile.

FFPE Samples are widely used in medical research for decades. It is a one of the most effective tool in clinical diagnostics and medical research to understand the biology of the human body and disease mechanisms. Check out Central Bio Hub’s most recent inventory if you're looking for high-quality FFPE specimens. With a variety of genetically distinct tumor tissue samples obtained from cancer patients, we unveils the largest collection of FFPE specimens. Our FFPE tissue samples were examined by pathologists to guide cutting-edge research on human tissues. Procure samples online.

https://centralbiohub.de/blogs/order-well-characterized-ffpe-samples-for-cancer-research