The invention by Manoj Jain (Kollagen Technology Products) Medifil II collagen particles provides an improved process for controlling the absorbency and other properties of collagen flakes. The process comprises using freeze-dried bovine collagen material and heating the freeze dried collagen material to a predetermined temperature range between 80 C. and 200 C. for a selected period of time. The collagen flakes will have an improved absorbency, density, porosity, and color. The porosity, absorbency, density and color of the collagen is selectively dependent upon the time and temperature used to heat the collagen flakes. The absorption of the collagen material is selected to be between two to twenty times the weight of the product, and the density of the collagen material is selected to be between 0.1 g/cc to 1.0 g/cc. The collagen flakes are ground into a powder after heating, for use as a wound dressing for moderate to high exudating wounds. )
Animal Wound Care Products Kollavet sheets particles gel collagen
Animal Wound Care Products
Collagen products are the foundation of wound healing. They act as a natural hemostat to immediately stop the bleeding. Faster healing is encouraged by increasing healthy granulation tissue formation and stronger and better-looking scars.
Animal Wound Care Products Kollavet sheets particles gel collagen Advanced Infected Treatment Benefits How To Apply Non Hydrolyzed
Advanced Wound Care DIY, How to, Treat, Dressing, Best Ways to, Tips
Making education a priority
Making education a priority for your wound condition will help you heal faster. Knowledge is power, and the more you know about your diagnosis, wound type, and how to take care of your wound, the better you will be able to manage your wound and the faster it will heal. You can learn more about skin and wound care-related topics from the list of patient education materials below. Our printer-friendly handouts make it easy to access and keep key resources at your fingertips.
Advanced Wound Care DIY, How to, Treat, Dressing, Best Ways to, Tips, What is, Fact Sheet, Diabetic Ulcer, Infection Control, Injury.
Wound Care Specialist and Expert: Healing Care by Human Biosciences
Discover the power of specialized wound care professionals at Human Biosciences. Our skilled experts’ techniques and personalized treatment plans to optimize your wound healing process.
Discover the power of specialized wound care professionals at Human Biosciences. Our skilled experts’ techniques and personalized treatment
Collagen Particles Medifil II Type 1 Collagen Properties Role Wound Healing Care Non-Hydrolyzed Advanced Products
Although collagen particles are not new to the market, they have recently become one of the most popular advanced wound care products, particularly among surgeons and podiatric physicians. Collagen particles can be incredibly useful as more physicians and wound care professionals explore more rapid and cost-efficient ways to improve wound healing.
What you remove from a wound (devitalized tissue) is still more significant than what you put on it. However, no matter what you put on a wound, proper wound debridement, offloading, and moisture balance are essential. Keeping a wound free of debris is still significant for wound healing. While the ease of use and low cost are the most evident advantages of collagen particles, the particle form of a collagen protein provides direct bioavailability for the wound bed, promoting wound healing.
Medifil® II Collagen Particles enable increased diffusion across the wound bed’s surface, in addition to quick absorption. The body’s natural tissue repair is stimulated by increased wound contact and bioavailability. A better understanding of collagen’s natural form and function in wound healing has aided practitioners in better understanding their wound healing options.
Medifil® II Collagen Particles are collagen in their “purest form”. Non-hydrolyzed collagen retains a higher percentage of its native triple helix protein structure, providing for greater molecular and scaffold stability during wound healing. To improve thermal endurance, mechanical strength, and the ability to engage in precise interactions with other biomolecules, collagen must maintain its triple helix form.
Type 1 collagen is required for the extracellular matrix to produce growth factors, as well as to store and retain growth factors. When the extracellular matrix is disrupted during hydrolysis, tissue loss and bacterial proliferation are possible. Because the aptitude of macrophages, fibroblasts, and endothelial cells to move and attach themselves is influenced by integrin interaction with collagen, type 1 collagen is required to recruit macrophages and monocytes. Remarkably, the strength of the chemotaxis stimulation is proportional to the amount of collagen present.
Metalloproteases like collagenase, as well as other types of trauma or enzymatic erosion, cause collagen degradation naturally. When this happens, however, the collagen fragments induce macrophage and fibroblast infiltration in the wound bed. Furthermore, the body recycles any exposed amino acids leftover from the fragmentation process and utilizes them to create new proteins for accelerated wound healing.
When collagen molecules fragment (hydrolyzed), their triple helix form is lost, the function shifts to a more rejuvenated condition by activating monocytes, resulting in the creation of more macrophages, and so on. Nonhydrolyzed collagen particles or powders may improve scaffolding and cell migration in forming granulation tissue. In the wound care market, there are many hydrolyzed collagen formats that do not compare to the high collagen protein structure and healing outcomes as do Medifil® II Collagen Particles.
Properties of Medifil® II Collagen Particles
Compatibility with topical treatments and various secondary dressings
Absorbent qualities
Hemostatic characteristics
Promotes angiogenesis
Faster healing rates
Lowers MMP levels prevalent in chronic wounds
Easy to use in undermining and tunneling
5-year shelf life
Clinical Indications of Medifil® II Collagen Particles
Acute and chronic wounds
Partial-thickness wounds
Full-thickness wounds
Non-infected and infected wounds
Light to moderately exudating wounds
Human BioSciences, Inc. blog offers education and tips; however,the information provided by this website or company is not a substitute for medical treatment or advice.
Collagen Sheets Skin Temp® II Advanced Wound Care Products Features Benefits How To Apply Healing Non-hydrolyzed type 1 bovine Native collagen
SkinTemp® II is Kollagen™ product that gives a wound both biological and physical qualities. SkinTemp® II is Kollagen™ in sheet form. The dressings are porous collagen membranes that are designed to be permeable and breathable, with fluid control similar to skin. They are flexible, pliable, elastic, and durable for ease of application. SkinTemp® II is 100% non-hydrolyzed type 1 bovine native collagen. Human BioSciences, Inc.’s proprietary Kollagen™ technology process protects and retains significantly more native triple helical protein structure, thus allowing superior stability of the molecule and scaffolding through all four phases of wound healing.
Advanced wound care solutions are focused on the wound’s microenvironment and are meant to maintain an ideal moist wound environment. Proper wound healing necessitates a moist wound healing environment. HBS uses a patented manufacturing technology called “KollagenTM” to create its native or aka non-hydrolyzed bovine type I collagen product.
SkinTemp® II Collagen Sheets are bioactive material products that interact with the wound microenvironment on a cellular and molecular level, assisting the body’s natural healing process. HBS’ native or aka non-hydrolyzed collagen is the “purest form” of collagen. Non-hydrolyzed collagen preserves a higher percentage of its native triple helix protein structure during wound healing, resulting in increased molecular and scaffold stability. Collagen must maintain its triple helix structure to improve heat endurance, mechanical strength, and the ability to engage in precise interactions with other biomolecules.
Application of Skin Temp® II Collagen Sheets
Cleanse the wound with a non cytotoxic wound cleanser.
Apply SkinTemp® II collagen sheet to wound bed surface, including any deeper areas.
Cover the wound with a large absorbent dressing to provide an advantageous healing environment.
Change the dressing based on the drainage amount.
Features & Benefits of SkinTemp® II Collagen Sheets
Easy application
Absorbs 40-60 times its weight in fluid
Accelerates healing
Balances the wound microenvironment
Higher protein structure of collagen
Mimic’s the body’s own collagen
Larger sizes available (7 x 7, 8 x 12
Indications include:
Minor wounds (shallow)
Major wounds (deep)
Arterial ulcers
Venous ulcers
Diabetic ulcers
Pressure wounds
Second-degree burns
Donor sites
Dehisced surgical wounds
Traumatic wounds
Warnings:
Do not use on third-degree burns
Do not use it in patients with bovine sensitivities.
Learn more www.humanbiosciences.com
Request samples https://humanbiosciences.com/prescription-products/
Human BioSciences, Inc. blog offers education and tips; however,the information provided by this website or company is not a substitute for medical treatment or advice.
Wound Re-epithelialization tissue Regeneration collagen Role care healing Process Phases Medifil SkinTemp Collatek Gel
Chronic wounds are a constant source of frustration for individuals and health care providers all around the world. Lower extremity wound chronicity affects an amazing 4.5 million persons in the United States, whereas all sorts of chronic wounds afflict an estimated 1% of the Western population. The wound healing cascade does not always follow an ordered pattern of hemostasis, inflammation, proliferation, and remodeling.
Healing phases occur in an ordered and timely manner in an ideal wound environment (hemostasis, inflammatory, proliferative, remodeling). Chronic or difficult-to-heal wounds, on the other hand, do not heal, and the wound healing comes to a stop. Collagen is a unique triple helix protein molecule that forms a key segment inside the extracellular matrix and plays a critical function in every wound healing phase (ECM). Chronic wounds become “stalled” in the inflammatory phase, with an increase in proteolytic enzymes and extracellular matrix destruction (ECM). This wound environment becomes hyperinflammatory and proteolytic, preventing the wound from advancing farther along the wound healing timeline.
Clinical evidence suggests that collagen-based dressings may be capable of influencing wound biochemistry and addressing chronic wound imbalances. Consider the type and source of collagen, as well as the dressing’s characteristics, format, and bioactive technology, when choosing an advanced wound care collagen dressing.
Wound Care Products with Collagen
Collagen is the most prevalent protein in the body. Collagen helps wounds heal by attracting fibroblasts and encouraging the formation of new collagen in the wound bed. By accelerating the proliferation, migration, and differentiation of keratinocytes and restoring the protection of the underlying dermal structures, the reepithelialization process results in the development of new epithelium and skin appendages.
Collagen dressing technology encourages autolytic debridement, angiogenesis, and reepithelialization while stimulating new tissue growth. Excessive matrix metalloproteinases (MMPs) form in chronic wounds, interfering with the normal wound healing process. Excessive MMPs detected in the extracellular matrix are bound and inactivated by collagen dressings (ECM). Keratinocytes continue to proliferate around the margins of the wound and migrate to cover it until they meet in the middle. Some sources claim that well-approximated wounds can re-epithelialize in as little as 48 hours, while others claim that the process takes 2 to 3 weeks.
When the reepithelialization process fails, the wound and the patient may suffer undesirable consequences, such as the formation of a hypertrophic scar. It’s critical to reduce irregularities in the healing process in order to facilitate reepithelialization and wound closure. Many conditions, including those stated above, can produce wounds with poor reepithelialization, as well as diabetes, trauma, burns, bacterial infections, tissue hypoxia, local ischemia, exudates, and high amounts of inflammatory cytokines generating a continuous state of inflammation. A persistent state of inflammation may lead to an increase in cellular senescence and decrescence in the cell pool. What we do know is that MMPs must be present in the appropriate amount, at the right time, and in the right place for a wound to heal properly.
Collagen, especially types I and II, makes up around 70-80 percent of the ECM of skin. Collagen can come from any species, but it’s most commonly found in bovine, porcine, equine, Piscean, and avian tissues. Type I collagen is the most common of the three collagen types. It is the most often employed collagen in the wound healing process, accounting for more than 90% of the tissue. It can also be found in tendons, ligaments, bones, teeth, and scar tissue, in addition to the skin. At all anatomic sites studied, the application of bovine collagen matrix resulted in faster wound healing than typical second intention healing. The average time to complete healing using bovine collagen matrix was 6.1 weeks, compared to 9.4 weeks in the control group. The core collagen-based products of Human BioSciences, Inc. USA using a gentle manufacturing technique referred to as Kollagen Technology are made entirely of Type I bovine collagen in its purest form.
Medifil® II is Kollagen™ in particle form
SkinTemp® II is Kollagen™ in sheet form
Collatek® Gel is collagen in a viscous gel form
These dressings are suitable for granulating wounds with light to moderate exudate. Collagen dressings absorb excess fluid while maintaining a moist environment that promotes healing. Sheets, particles, amorphous gels, and pads are all options for collagen dressings.
Collagen acts as a template for future tissue formation in its matrix structure, and the primary structure continues to attract fibroblasts to the region. When the healing process reaches the maturation stage, it is thought to boost the deposition of orientated collagen fibers, which increases the new tissue’s tensile strength.
The goal of wound closure requires wound reepithelialization. The development of new epithelium and skin appendages is part of the reepithelialization process, which is a multifactorial systemic process. A number of variables might stymie the epithelialization process, all of which must be addressed before wound healing progresses. Excess matrix metalloproteases, impaired fibroblast signaling, ECM instability, and halted keratinocyte migration are all common stalling reasons.
When used in conjunction with wound bed preparation, moist-wound healing, offloading/redistribution, and education, different Collagen technology dressings have been found to advance chronic complex wounds towards the wound healing trajectory. When choosing advanced wound care products, healthcare providers should evaluate quality, product features, pricing, and availability.
References
Kolenik SA 3rd, McGovern TW, Leffell DJ. Use of a lyophilized bovine collagen matrix in postoperative wound healing. Dermatol Surg. 1999 Apr;25(4):303-7. doi: 10.1046/j.1524-4725.1999.08230.x. PMID: 10417587.
Brenner M, Albert P, Raminfard A. Collagen Treatment in the Diabetic Foot. The Diabetic Foot. 2019 November/December. Podiatry Management. https://podiatrym.com/pdf/2019/11/Brenner1119Web.pdf last accessed September 13, 2021.
Gibson DJ, Schultz GS. Molecular Wound Assessments: Matrix Metalloproteinases. Adv Wound Care (New Rochelle). 2013;2(1):18-23. doi: 10.1089/wound.2011.0359
Chattopadhyay S, Raines RT. Review collagen-based biomaterials for wound healing. Biopolymers. 2014;101(8):821-833. doi: 10.1002/bip.22486 Xenogeneic extracellular matrix as a scaffold for tissue reconstruction.
Badylak SF Transpl Immunol. 2004 Apr; 12(3-4):367-77. Westgate, S., Cutting, K. F., Deluca, G., &
Assad, K. (n.d.). Collagen dressings Made Easy (page 1 of 3) › Made Easy › Wounds UK. Retrieved September 13 ,2021 from http://www.wounds-uk.com/made-easy/collagen-dressings-made-easy.
Ayello E.A., Baranoski S., Kerstein M.D., Cuddigan J. Wound treatment options. In: Baranoski S., Ayello E.A., editors. Wound Care Essentials: Practice Principles. Lippincott Williams & Wilkins; Philadelphia, PA: 2003. p. 138 León-López A, Morales-Peñaloza A, Martínez-Juárez VM, Vargas-Torres A, Zeugolis DI, Aguirre-Álvarez G.
Hydrolyzed Collagen-Sources and Applications. Molecules. 2019;24(22):4031.Published 2019 Nov 7. doi:10.3390/molecules24224031
Fleck CA, Simman R. Modern collagen wound dressings: function and purpose. J Am Col Certif Wound Spec. 2011;2(3):50-54. Published 2011 Aug 1. doi: 10.1016/j.jcws.2010.12.003
V. R. Krishnaswamy and P. S. Korrapati, “Role of Dermatopontin in re-epithelialization: implications on keratinocyte migration and proliferation,” Scientific Reports, vol. 4, p. 7385, 2014.
Human BioSciences, Inc. blog offers education and tips; however,the information provided by this website or company is not a substitute for medical treatment or advice.
Collagen Particle Advanced Wound Care Healing Product Application Features Benefits Advantages non-hydrolyzed Type 1 bovine Medifil
Medifil® II Collagen Particles is a KollagenTM product that gives a wound both biological and physical qualities. The particles have a large surface area, allowing them to effectively penetrate the wound surface and release the maximum quantity of collagen. Medifil® II is a non-hydrolyzed type 1 bovine native collagen that is 100% non-hydrolyzed. This technology approach developed by Human BioSciences, Inc. protects and retains considerably more native triple helical protein structure, providing for enhanced molecule and scaffold stability during all four phases of wound healing.
Advanced wound care solutions are focused on the wound’s microenvironment and are meant to maintain an ideal moist wound environment. Proper wound healing necessitates a moist wound healing environment. HBS uses a patented manufacturing technology called “KollagenTM” to create its native or aka non-hydrolyzed bovine type I collagen product.
Medifil® II Collagen Particles are bioactive material products that interact with the wound microenvironment on a cellular and molecular level, assisting the body’s natural healing process. HBS’ native or aka non-hydrolyzed collagen is the “purest form” of collagen. Non-hydrolyzed collagen preserves a higher percentage of its native triple helix protein structure during wound healing, resulting in increased molecular and scaffold stability. Collagen must maintain its triple helix structure to improve heat endurance, mechanical strength, and the ability to engage in precise interactions with other biomolecules.
Application of Medifil® II Collagen Particles
Cleanse the wound with a non cytotoxic wound cleanser, extending to the surrounding skin.
Apply Medifil® II particles ¼ inch to the entire wound bed surface, including any deeper areas.
Cover the wound with an absorbent dressing to provide an advantageous healing environment.
Change the dressing based on the drainage amount.
Features & Benefits of Medifil® II Collagen Particles
Absorbs 40-60 times its weight in fluid
Accelerates healing
Balances the wound microenvironment
Higher protein structure of collagen
Mimic’s the body’s own collagen
Easy pour vial in compliance with infection control
Indications include:
Minor wounds (shallow)
Major wounds (deep)
Arterial ulcers
Venous ulcers
Diabetic ulcers
Pressure wounds
Second-degree burns
Donor sites
Dehisced surgical wounds
Traumatic wounds
Warnings:
Do not use on third-degree burns
Do not use it in patients with bovine sensitivities.
Learn more www.humanbiosciences.com
Request samples https://humanbiosciences.com/prescription-products/
Human BioSciences, Inc. blog offers education and tips; however,the information provided by this website or company is not a substitute for medical treatment or advice.
Venous leg ulcers Treatment Products Collagen Particle Sheet Gel Medifil Collagen Skin Temp Collatek How to Apply
Venous leg ulcers (VLUs) are caused by blood leaking from veins into the skin, causing the skin to break down or produce an ulcer a hole in the skin forms when blood does not flow through the veins as it should. Both men and women are affected by vascular disease. VLUs are more likely among people who have had a leg injury, have varicose veins or clots in their legs, have had many pregnancies, are obese, or have a job that requires long periods of standing or sitting.
Wearing fitted compression stockings and elevating your legs above your heart are two things you can do to improve or manage venous insufficiency. This will assist in returning blood to the heart. If you wear compression stockings, you should change them every 6 months because they will stretch out over time. The progressive compression won’t be enough. When seated, avoid crossing your legs, and if you must stand for long periods of time at work, shift your weight from one foot to the other. Tight apparel, shoes, garters, girdles, and knee-high socks should all be avoided.
Healing venous leg ulcers (VLUs) frequently reopen. Living a healthier lifestyle, hydrating skin daily, preserving the skin, and maintaining excellent circulation can all assist to prevent ulcers from reappearing (wearing prescribed compression therapy).
Collagen dressings, when used in conjunction with compression therapy bandaging, have been shown to be beneficial in the treatment of difficult-to-heal venous leg ulcers. This also improves the patient’s quality of life.
Collagen Dressing Technology Matters
The purpose of collagen technology dressings is to inhibit protease activity while healing the wound. Collagen advanced wound care dressings are shown to be a catalyst in wound chronicity by promoting tissue growth, autolysis, angiogenesis, collagen deposition, and wound re-epithelialization. KollagenTM Technology, a unique manufacturing technology developed by Human BioSciences, Inc. (HBS), is used to create HBS products. The collagen triple helix protein molecule shape is retained and kept in its “purest” form through our carefully planned production process, resulting in the best grade collagen products. Understanding functional features such as biomolecular biological activity and modalities are critical when choosing the right collagen dressing and technology. KollagenTM Technology from HBS is the “only” intact collagen product available in the tissue regeneration industry.
Human BioSciences’s (HBS) collagen is made entirely of non-hydrolyzed type I bovine (cattle) collagen. Non Hydrolyzed collagen preserves substantially more of its native triple helix form, providing for improved molecular stability and scaffolding as wounds progress toward healing. Human BioSciences, Inc. has meticulously bioengineered a patented KollagenTM technology approach to ensure collagen molecules preserve bioactivity and remain in their purest form, binds, and inactivates excessive MMPs present in chronic wounds.
Properties and Features of Medifil® II Collagen Particles, Skin Temp® II Collagen Sheets, and Collatek® Gel
Compatibility with topical treatments and various secondary dressings
Absorbent qualities
Hemostatic characteristics
Promotes angiogenesis
Faster healing rates
Lowers MMP levels prevalent in chronic wounds
Cuttable – collagen sheets
Easy to use in undermining and tunneling – collagen particles
Compatible with topicals and dressings
Available in a variety of sizes
5-year shelf life
Clinical Indications of Medifil® II Collagen Particles, Skin Temp® II Collagen Sheets, and Collatek® Gel
Acute and chronic wounds, partial and full-thickness wounds
Non-infected and infected wounds
Light to moderately exudating wounds
Do not use on third-degree burns
Sensitivities to bovine products
Application of Medifil® II Collagen Particles, Skin Temp® II Collagen Sheets, and Collatek® Gel
The application is simple, and the product is compatible with other topical agents and dressings. If deeper wounds have undermining or tunneling, gently press the product into the spaces loosely.
The frequency of dressing changes is determined by the wound assessment, amount of exudate, physician order, and dressing manufacturer requirements. Depending on the dressing, several wear times, such as 1-7 days, may be offered. A secondary dressing, such as transparent film, composite, hydrocolloid, gauze, or foam, is required for most wounds.
The goal is to provide evidence-based advanced wound care while adhering to established and developed medical standards in order to achieve the best possible wound healing results.
References
Brenner M, Albert P, Raminfard A. Collagen Treatment in the Diabetic Foot. The Diabetic Foot. 2019 November/December. Podiatry Management. https://podiatrym.com/pdf/2019/11/Brenner1119Web.pdf last accessed September 17, 2020.
Gibson DJ, Schultz GS. Molecular Wound Assessments: Matrix Metalloproteinases. Adv Wound Care (New Rochelle). 2013;2(1):18-23. doi: 10.1089/wound.2011.0359
Xenogeneic extracellular matrix as a scaffold for tissue reconstruction. Badylak SF Transpl Immunol. 2004 Apr; 12(3-4):367-77. Westgate, S., Cutting, K. F., Deluca, G., & Assad, K. (n.d.).
Collagen dressings Made Easy (page 1 of 3) › Made Easy › Wounds UK. Retrieved September 17,2020 from http://www.wounds-uk.com/made-easy/collagen-dressings-made-easy.
Ayello E.A., Baranoski S., Kerstein M.D., Cuddigan J. Wound treatment options. In: Baranoski S., Ayello E.A., editors. Wound Care Essentials: Practice Principles. Lippincott Williams & Wilkins; Philadelphia, PA: 2003. p. 138
León-López A, Morales-Peñaloza A, Martínez-Juárez VM, Vargas-Torres A, Zeugolis DI, Aguirre-Álvarez G. Hydrolyzed Collagen-Sources and Applications. Molecules. 2019;24(22):4031. Published 2019 Nov 7. doi:10.3390/molecules24224031
Fleck CA, Simman R. Modern collagen wound dressings: function and purpose. J Am Col Certif Wound Spec. 2011;2(3):50-54. Published 2011 Aug 1. doi: 10.1016/j.jcws.2010.12.003
Wound Care Gel Collatek Non-Hydrolyzed Type 1 Bovine Advance Product Application Features Benefits Healing Treatment
Collatek® II Collagen Gel is a KollagenTM product that gives a wound both biological and physical qualities. Collatek® Gel is collagen in the form of a viscous gel. Collatek® is a sterile collagen gel that promotes wound healing by donating moisture to the wound, without causing maceration. Collatek® II Collagen Gel is to be applied generously to the affected area. It is ideal for hard-to-reach areas like undermining and tunneling in deeper wounds.
Advanced wound care solutions are focused on the wound’s microenvironment and are meant to maintain an ideal moist wound environment. Proper wound healing necessitates a moist wound healing environment. HBS uses a patented manufacturing technology called “KollagenTM” to create its native or aka non-hydrolyzed bovine type I collagen product.
Collatek® II Collagen Gel is a bioactive material product that interacts with the wound microenvironment on a cellular and molecular level, assisting the body’s natural healing process. HBS’ native or aka non-hydrolyzed collagen is the “purest form” of collagen. Non-hydrolyzed collagen preserves a higher percentage of its native triple helix protein structure during wound healing, resulting in increased molecular and scaffold stability. Collagen must maintain its triple helix structure to improve heat endurance, mechanical strength, and the ability to engage in precise interactions with other biomolecules.
Application of Collatek® II Collagen Gel
Cleanse the wound with a non cytotoxic wound cleanser.
Apply Collatek® II collagen gel generously to the wound bed surface, including in any undermining and or tunneling.
Cover the wound with a secondary absorbent dressing to provide an advantageous healing environment.
Change the dressing every day.
Features & Benefits of Collatek® II Collagen Gel
Viscous gel and can be used as a wound filler
Donates moisture without causing maceration
Cost-effective
Jump starts healing
Balances the wound microenvironment
Higher protein structure of collagen
Mimic’s the body’s own collagen
Indications include:
Minor wounds (shallow)
Major wounds (deep)
Arterial ulcers
Venous ulcers
Diabetic ulcers
Pressure wounds
Second-degree burns
Donor sites
Dehisced surgical wounds
Traumatic wounds
Warnings:
Do not use on third-degree burns
Do not use it in patients with bovine sensitivities.
Learn more www.humanbiosciences.com
Request samples https://humanbiosciences.com/prescription-products/
Human BioSciences, Inc. blog offers education and tips; however,the information provided by this website or company is not a substitute for medical treatment or advice.
Complex wounds like arterial ulcers, venous ulcers, diabetic ulcers, and pressure ulcers require a multidisciplinary team working together to impact optimized healing. These wounds are oftentimes a challenge for both the patient and clinician due to the chronicity where there is an inability to heal the wound, risks of infection, and managing the associated systemic disorders. Not to mention, the substantial burden on the healthcare industry with costs exceeding $10 billion annually in North America.
Various modalities are sometimes necessary to achieve healing with chronic or hard-to-heal wounds, as mentioned. Negative pressure wound therapy (NPWT) is a technology that has been used in the management and treatment of surgical and various other wound etiologies. NPWT is a type of therapy that decreases air pressure on the wound by using an application of sub-atmospheric pressure to assist in wound management. NPWT has been shown to enhance healing and improve the progression rate of new tissue formation, decreasing swelling and bacterial burden in wounds.
It has been reported that the use of collagen dressings in conjunction with other treatment modalities like negative pressure wound therapy (NPWT) can help enhance healing. Collagen has been used as a catalyst for wound healing in patients with wound chronicity due to the crucial component of the extracellular (ECM) during healing and tissue remodeling. However, collagen plays a major role in all four phases of wound healing; Hemostasis, Inflammatory, Proliferative, and Remodeling.
When NPWT and collagen dressing treatments are paired together, they help generate new granulation tissue, clearing degenerative fibrous tissue, scaffold osteoblasts, and moving complex wounds towards a healing trajectory. Combining collagen dressings and NPWT requires a 3-day a week dressing change. Wound cleansing, application of the collagen dressing including in deeper areas, NPWT foam dressing application, supports a moist wound healing environment and advantageous wound microenvironment to optimize healing outcomes.
When challenged with chronic or hard-to-heal wounds, it is important to remember that regular monitoring of the wound, along with various treatment modalities may be indicated as appropriate to help shorten the length of healing time and reduce patient suffering.
Human BioSciences, Inc. blog offers education and tips; however,the information provided by this website or company is not a substitute for medical treatment or advice.
Factors Affecting Wound Healing What Are Slow Which Poor Chronic Diagnosis Tips Stages Food Instructions To Follow
The cause of a chronic wound or wound that has not healed in over 30 days, must be determined in order to control the underlying issues. A chronic wound is also explained as a skin wound that does not heal, heals slowly, or heals but recurs. Trauma, burns, skin malignancies, infection, or underlying medical disorders such as diabetes are only a few of the various reasons for chronic (ongoing) skin wounds. Wounds that take a long time to heal require extra attention.
If a leg or foot ulcer is caused by diabetes, for example, your doctor may check your blood sugar control and may recommend that you see a podiatrist to prevent further ulcers. Surgical treatment of the varicose veins may be indicated in the case of an ulcer caused by varicose veins. A chronic wound can be diagnosed using a variety of ways, including:
The following are some of the factors that can impede the healing of a wound:
Dead skin (necrosis) – foreign elements and dead skin obstruct the healing process.
Infection – a bacterial infection can occur in an open wound. Rather than mending the wound, the body attacks the infection.
Continuous bleeding will keep the wound borders apart if you have a hemorrhage.
Mechanical harm — a person who is immobile, for example, is a danger of developing bed sores due to persistent pressure and friction.
Poor dietary choices may deny the body of nutrients necessary for wound healing, such as vitamin C, zinc, and protein.
Medical illnesses that restrict blood supply to the area, such as diabetes, anemia, and some vascular diseases, or any problem that impairs the immune system.
Age – Wounds in the elderly tend to take longer to heal.
Medicines – some drugs or therapies used to treat specific medical diseases can obstruct the body’s natural healing process.
Tobacco use — Tobacco use slows healing and raises the risk of problems.
Varicose veins — skin breakdown and ulceration can occur as a result of restricted blood flow and swelling.
Dryness – lesions exposed to the air (such as leg ulcers) are less likely to heal. The numerous cells that play a role in healing, such as skin cells and stem cells
Methods of Diagnosis
Examining the wound and assessing the local nerve and blood supply are all part of the physical examination.
Medical history, including chronic medical issues, recent surgery, and medications you regularly use or have recently taken
Tests of the blood and urine
A wound biopsy was performed.
Culture the wound to check for disease-causing microorganisms (pathogenic).
Suggestions for Self-Care
Follow your doctor’s instructions, but for slow-healing wounds, avoid using drugs that interfere with the body’s natural healing process if at all feasible.
Anti-inflammatory medicines, such as over-the-counter aspirin, for example, inhibit immune system cell function. In the short term, ask your doctor for a list of medicines to avoid.
Make sure you eat well. To aid in the healing process, your body requires healthy nutrition.
Include vitamin C-rich foods in your diet. Vitamin C is required for the production of collagen in the body. Vitamin A, copper, and zinc are all necessary elements for wound healing, and they may all be found in fresh fruits and vegetables. Supplementing your diet with extra vitamin C may be beneficial.
Maintain the dressing on your wound. If wounds are kept warm, they heal faster. When changing dressings, try to be as rapid as possible. A wound’s temperature can drop when exposed to the open air, which can impede healing for a few hours.
On a chronic wound, avoid using antiseptic lotions, washes, or sprays. The cells involved in wound healing are poisoned by these preparations.
Exercise on a regular basis enhances blood flow, improves general health, and accelerates wound healing. Consult your doctor for workout recommendations.
Any chronic medical issues, such as diabetes, should be managed.
Smoking is not permitted.
Consult your Physician
Check your wound on a regular basis. If you develop any of the following symptoms, see your doctor right away:
Bleeding
Increased drainage or pus
Your wound is becoming more painful
Fever
If you have any worries regarding your wound, always see your doctor
Human BioSciences, Inc. blog offers education and tips; however,the information provided by this website or company is not a substitute for medical treatment or advice.
Collagen Wound Healing Supplements Best Protect Skin Preventive Types of Role of Early Stages Protect Skin From Skin Injury Tear
As we become older, the skin becomes thinner and less elastic, making it more prone to damage. Aging causes a decrease in fibroblasts, collagen synthesis, and an increase in collagen degradation. Skin will become more dry, making it impair the skin’s barrier function. Collagen loss starts between 18 and 29 years old. After age 40, collagen loss is approximately one percent loss a year. By the age 80, collagen loss can decrease up to 75 percent.
Studies show that nutritional supplements containing collagen peptides can help reduce skin vulnerability in the elderly therefore, be considered a preventative in conditions like skin tears. Collagen acts as a scaffold in our connective tissues. This is normally in its type I, II, and III forms. Type III collagen is laid down first in the early stages of wound healing. Type I collagen then increases during scar formation and remodeling. Intake of collagen peptides (highly absorbable) show therapeutic effects for pressure injuries, but it is unknown whether they can protect the skin from pressure injuries.
Human BioSciences, Inc. blog offers education and tips; however,the information provided by this website or company is not a substitute for medical treatment or advice.