happy out of touch melshi thursday to all those who celebrate
Claire Keane
we're not kids anymore.
ojovivo
Jules of Nature
No title available
PUT YOUR BEARD IN MY MOUTH
taylor price
I'd rather be in outer space 🛸

Origami Around
hello vonnie
Misplaced Lens Cap
sheepfilms

roma★

★
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One Nice Bug Per Day

Kaledo Art

oozey mess

pixel skylines

ellievsbear
seen from India

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@major-comet
happy out of touch melshi thursday to all those who celebrate
me explaining rtvs lore to my non rtvs fan friends
my fellow queers. happy pride month. Past 2 years ive made pride headers for diff flags but i didnt have time this year (due to recent news) so i made one big flag à la NASA. Tried to cover most destinations in D2!
Completely lost all concepts of joke comprehension for a moment because my instinct was to register this as a new type of kitchencel
Id love to see the trans flag with rvb characters <3
Two Versions, because I couldn't decide what to do with Wyoming. Thank you for the suggestion, this one might be my favorite.
if you vote me for president i vow to make everything the ocean again. no more land only ocean. this will solve all of our problems and replace them with new, far more interesting problems
it boggles the mind how i manage to have so many performance issues with halo reach - an xbox 360 title - in the master chief collection even on the lowest graphics settings, but my computer runs destiny 2 pretty much perfectly on medium-high graphics settings. what the fuck did they do to halo reach
adder in a bunch of cute dresses :) thank you for all the recs!
and bonus yuri rustedtracks <3
For millions of people managing type 2 diabetes, mornings begin the same way — a needle, a dose, and a quiet mental note to do it all again
For millions of people managing type 2 diabetes, mornings begin the same way — a needle, a dose, and a quiet mental note to do it all again tomorrow.
That routine just changed.
On March 26, 2026, the U.S. Food and Drug Administration approved Awiqli (insulin icodec-abae), developed by Novo Nordisk, as the first and only once-weekly basal insulin ever approved for adults with type 2 diabetes in the United States.
This is not a minor update to an existing drug.
It is the first entirely new class of basal insulin to reach U.S. patients in more than two decades.
Instead of injecting insulin every single day, people with type 2 diabetes using Awiqli will only need one shot per week, on the same day, every week.
That means reducing from 365 injections a year down to just 52.
For anyone who has ever felt the weight of that daily ritual — the anxiety of forgetting, the physical discomfort, the constant reminder that their body needs help — this approval represents something much bigger than a dosing schedule.
It represents relief.
How the Drug Actually Works
Understanding why this injection lasts a full week requires a quick look inside the body.
Most traditional basal insulins are absorbed into the bloodstream and begin breaking down within 24 hours, which is why patients need a fresh dose every day to maintain stable blood sugar levels.
Awiqli works differently.
Its active ingredient, insulin icodec-abae, is engineered to loosely attach to a blood protein called albumin, which is found naturally and abundantly in the bloodstream.
This attachment creates a slow-release reservoir.
Instead of flooding the system and fading fast, the insulin releases gradually and consistently over an entire seven-day period, keeping blood sugar in a healthy range around the clock...
The FDA reviewed and ultimately declined to approve it for people with type 1 diabetes, citing concerns about a modestly increased risk of hypoglycemia in that population specifically.
Some regulatory agencies in other countries, including the European Union, Canada, Australia, and Japan, have approved Awiqli for both type 1 and type 2 diabetes, but for now the U.S. approval is limited to type 2...
What Comes Next
Awiqli is not standing alone in this space for long.
Eli Lilly is developing its own once-weekly basal insulin, called efsitora alfa, which is currently in late-stage clinical trials.
If that drug also earns FDA approval, it would give patients and doctors two once-weekly options to choose from, allowing for personalized decisions based on a patient’s health profile, insurance coverage, and individual response.
The broader direction of travel in diabetes care is unmistakable.
Fewer injections, smarter formulations, and better integration with digital tools like continuous glucose monitors and insulin-tracking apps are all converging toward a future where managing diabetes requires less daily mental effort without becoming any less medically precise...
A Small Shot With Large Implications
It is easy to look at a once-weekly injection and see only a scheduling change.
But the science behind Awiqli, the scale of the ONWARDS trials, and the consistent satisfaction reported by patients all point toward something that matters far more than convenience.
Diabetes management has always asked a lot of people.
It asks for daily vigilance, daily discipline, and a daily willingness to confront one’s own condition, sometimes in uncomfortable or inconvenient circumstances.
Anything that reduces that load, without reducing the quality of care, is worth taking seriously.
For the more than 37 million Americans living with diabetes, and the hundreds of millions more around the world, a simpler weekly routine could mean the difference between a treatment plan that works on paper and one that actually works in a person’s life.
That is the real significance of what the FDA approved on March 26, 2026.
Not just a new drug.
A new way of keeping people healthy, one week at a time.
-via Science Aim, March 29, 2026.
When people argue that food from Chinese and Mexican restaurants in the US are not 'real' representations of that culture's cuisine ignore the historical reality that these dishes were developed by diasporic communities striving to recreate the flavors of home with available resources. Such criticism frames adaptation as a loss of authenticity, rather than recognizing it as a sincere and evolving expression of culture by people separated from their homeland.
Too good to leave in the tags
German Windows:
so last year during a period of intense suicidal depression i made this necklace that i always wear, right, and the thing is it's genuinely brought me a lot of comfort and relief and i've developed a strong sentimental attachment to it, to the point that i can inarguably state that it's had a net positive effect on my mental wellbeing. however i did now just have to stop to almost throw up laughing because i realised that i've succumbed to the amulet.
Its good that i have a blog now cuz I used to write all this bullshit down physically in a diary and my mom found mine and read it when i was 15 and i got in so much trouble cuz i drew goku with a boner so foreboding frightening it cleaved his jorts clean in half down the crotch seam and she threw it in a dumpster but then i crawled inside and retrieved it in the dark of night to preserve the archives of my mind but I lost it the very next day cuz i dropped it into the wave pool at Wild Wild n Wet (waterpark). Nowadays relying on digital spaces we have no guarantee of our eras information being preserved for futture generations tho and as the lights go out The silence will be suffocating and we will all be boner goku at the bottom of the wave pool at Wild Wild and Wet lowkey so u might as well start an nsfw twitter with ur government name and credit card info in bio tbh
the amount of breathing room you gave my post in the speech bubble is fucking with me interior design feng shui style
you learn something new everyday. unless you're a historian. then you learn something old
heartbreaking: barely a week after the announcement of the end of live service and with a sequel seeming extremely unlikely, local gamer’s relatively casual destiny 2 enjoyment starts to veer dangerously close to hyperfixation territory