A very cute piece of art! It shows a stack of several round daruma dolls with bushy hair. The top one is painted in red and all the ones below are black.
The text on the right says 七転八起, read しちてんはっき. This is a common expression, and it can also be written 七転び八起き, read ななころびやおき.
七 means 7. It's read なな, なな.つ, なの, or シチ.
八 means 8. It's read や, や.つ, やっ.つ, よう, ハチ, or ハツ.
転 means to revolve, turn, change, or fall. Its most common readings are ころ (e.g.ころ.がる, ころ.げる,ころ.がす, or ころ.ぶ) and テン. It can also be read まろ.ぶ, うたた, うつ.る, or くる.めく.
起 means to rouse, wake, or get up. It's read お (e.g. お.きる, お.こる, お.こす), おこ.す, た.つ, or キ.
As you can guess, the literal meaning of the expression is "fall seven times, get up eight." It means never giving up, or keeping at something until you succeed. It can also refer to the ups and downs of life.
(For fun, replace the last character with 倒, meaning collapse, to get 七転八倒 [しちてんばっとう], meaning to writhe about in agony.)
Finally, the text on the left says 達磨之図 or だるまのず, which means a drawing of a daruma.