Alpha Relay
Mass relays are believed to be indestructible by galactic society, but no known attempts have been made to actually damage or destroy a relay because they are the only means of long distance space travel and thus are too vital to risk.
Dr. Amanda Kenson and her research team calculated that if a large enough mass impacts a relay with enough force, the relay should not be able to withstand it. The consequences of destroying a mass relay are immense: as a huge mass effect engine manipulating massive quantities of energy, a relay could produce an explosion of supernova proportions.
Following a botched rescue attempt for Dr. Kenson that turns into an attempt to delay the Reaper invasion, a large asteroid is purposely steered into the Bahak system's Alpha Relay. The resulting impact tears apart the relay, causing an explosion which annihilates the Bahak system and kills more than 300,000 inhabitants.
