The Buffalo Spree called Iroquois Brewing Company "Buffalo's greatest brewery." The successor of the Jacob Roos Brewery started in 1830 the Iroquois Brewing Company was one of Buffalo's oldest businesses being founded in 1842. Named after the Native American confederacy that held power in what is now Upstate New York the Iroquois Brewing Company was both a part of Buffalo's original brewing renaissance and the lead competitor after prohibition.
By the 1950's Iroquois employed 500 people, consisted of 40% of all beer being consumed in Buffalo, and advertised everywhere. In an attempt to compete with other national beers Iroquois beat out its local competitors and joined a conglomeration with a distribution system across 8 states. However, 129 years after it was founded Iroquois shuttered its doors in 1971 unable to compete with megabrewer prices. Today the Iroquois Brewing Company remains a powerful specter of Buffalo's past along with Bethlehem Steel, the Larkin Administration Building, The Rockpile, and the Erie Canal.