CALB2 mediates tumor progression and immune escape in colorectal cancer by shaping an inhibitory immune microenvironment - Research
Background: Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide, characterized by a highly immunosuppressive tumor microenvironment (TME) that facilitates immune evasion and tumor progression. Methods: Integrated analysis of TCGA and GEO datasets was performed to evaluate CALB2 expression and its prognostic significance in CRC. Functional experiments including…














